מדינה: ארצות הברית
שפה: אנגלית
מקור: NLM (National Library of Medicine)
FUROSEMIDE (UNII: 7LXU5N7ZO5) (FUROSEMIDE - UNII:7LXU5N7ZO5)
MWI
FUROSEMIDE
FUROSEMIDE 10 mg in 1 mL
ORAL
PRESCRIPTION
A diuretic-saluretic for prompt relief of edema. Furosemide Syrup 1% is an effective diuretic possessing a wide therapeutic range. Pharmacologically it promotes the rapid removal of abnormally retained extracellular fluids. The rationale for the efficacious use of diuretic therapy is determined by the clinical pathology producing the edema. Furosemide Syrup 1% is indicated for the treatment of edema (pulmonary congestion, ascites) associated with cardiac insufficiency and acute noninflammatory tissue edema. The continued USB of heart stimulants, such as digitalis or its glycosides, is indicated in cases of edema involving cardiac insufficiency. Furosemide Syrup 1% is a highly effective diureticsaluretic which if given in excessive amounts may result in dehydration and electrolyte imbalance. Therefore, the dosage and schedule may have to be adjusted to the patients' needs. The animal should be observed for early signs of electrolyte imbalance, and corrective measures administered. Early signs of electrolyte im
Furosemide Syrup 1% (10 mg/mL), available in 60 mL bottles with calibrated safety dropper.
Abbreviated New Animal Drug Application
FUROSEMIDE 1%- FUROSEMIDE SYRUP MWI ---------- FUROSEMIDE SYRUP 1% ORAL SYRUP (10 mg/mL) WITH CALIBRATED SAFETY DROPPER FOR USE IN DOGS ONLY NOT FOR USE IN HUMANS KEEP OUT OF REACH OF CHILDREN CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. Approved by FDA under ANADA # 200-373 A DIURETIC-SALURETIC FOR PROMPT RELIEF OF EDEMA. DESCRIPTION: Furosemide Syrup 1% is a chemically distinct diuretic and saluretic pharmacodynamically characterized by the following: 1) A high degree of efficacy, low-inherent toxicity and a high therapeutic index. 2) A rapid onset of action of comparatively short duration. 3) A pharmacologic action in the functional area of the nephron, i.e., proximal and distal tubules and the ascending limb of the loop Henle. 4) A dose-response relationship and a ratio of minimum to maximum effective dose range greater than ten fold. 5) It is administered orally. It is readily absorbed from the intestinal tract and well tolerated. The CAS Registry Number is: 54-31-9. This product contains alcohol 11.5% USP as a preservative, and FD&C Yellow #6 and D&C Yellow #10 as color additives. Furosemide Syrup 1%, a diuretic, is an anthranilic acid derivative with the following structural formula: 1,2 2,4 1,2 Generic name: Furosemide (except in United Kingdom-frusemide). Chemical name: 4- chloro-N-furfuryl-5-sulfamoylanthranilic acid. ACTIONS The therapeutic efficacy of Furosemide Syrup 1 % is from the activity of the intact and unaltered molecule throughout the nephron, inhibiting the reabsorption of sodium not only in the proximal and distal tubule, but also in the ascending limb of the loop of Henle. The prompt onset of action is a result of the drug's rapid absorption and a poor lipid solubility. The low lipid solubility and a rapid renal excretion minimizes the possibility of lipid accumulation in tissues and organs or of crystalluria. Furosemide Syrup 1 % has no inhibitory effect on carbonic anhydrase or aldosterone activity in the distal tubule. The drug possesses קרא את המסמך השלם