Fluimucil 200mg Granules for Solution

מדינה: פיליפינים

שפה: אנגלית

מקור: FDA (Food And Drug Administration)

מרכיב פעיל:

Acetylcysteine

זמין מ:

The Cathay Drug Co., Inc.; Distributor: The Cathay Drug Co., Inc.

INN (שם בינלאומי):

Acetylcysteine

כמות:

200mg

טופס פרצבטיות:

Granules for Solution

יחידות באריזה:

Sachet x 1 g (box of 30 sachets)

תוצרת:

Zambon Switzerland Ltd., Switzerland

תאריך אישור:

2022-03-21

עלון מידע

FLUIMUCIL 200 MG GRANULES FOR SOLUTION
(ACETYLCYSTEINE )
MUCOLYTIC
Category: Oral
DESCRIPTION
THE CATHAY DRUG CO., INC.
PRODUCT DESCRIPTION
Acetylcysteine (Fluimucil) 200 mg is a yellow granulate with a
characteristic orange, slightly
sulphureous odour.
FORMULATION
Each sachet contains:
Acetylcysteine, Ph. Eur ………………… 200 mg
PHARMACOLOGY
Acetylcysteine, active ingredient of FLUIMUCIL, exerts an intensive
mucolytic-fluidifying action
on mucous and mucopurulent secretions by depolymerizing the
mucoproteic complexes and the
nucleic acids which confer viscosity to the vitreous and purulent
component of the sputum and
other secretions.
Furthermore, acetylcysteine exerts a direct antioxidant action, having
a free thiol (-SH) nucleophilic
group which is able to interact directly with the electrophilic group
of the oxidant radicals. Of
particular interest is the recent finding that acetylcysteine protects
α1-antitrypsin enzyme inhibiting
elastase from the inactivation by hypochlorous acid (HOCl), a powerful
oxidant agent produced by
the myeloperoxidase enzyme of activated phagocytes.
These features make ACETYLCYSTEINE (FLUIMUCIL) particularly suitable
for the treatment of
acute and chronic affections of the respiratory system, characterized
by thick, viscous mucous and
mucopurulent secretions.
In addition, due to its molecular structure, acetylcysteine can easily
cross the cellular membranes.
Inside the cell, acetylcysteine is deacetylated to L-cysteine, an
amino acid indispensable for the
glutathione synthesis (GSH).
GSH is a highly reactive tripeptide found ubiquitously in the various
tissues of animal and is
essential for the maintenance of functional capacity as well as
cellular morphological integrity. It
represents the most important protective endocellular mechanism
against oxidant radicals, either of
external or internal nature, as well as toward numerous cytotoxic
substances.
Acetylcysteine plays a role of primary importance in the maintenance
of adequate GSH levels
contributing to the cellular pr