EPINEPHRINE injection, solution

מדינה: ארצות הברית

שפה: אנגלית

מקור: NLM (National Library of Medicine)

מרכיב פעיל:

EPINEPHRINE (UNII: YKH834O4BH) (EPINEPHRINE - UNII:YKH834O4BH)

זמין מ:

American Regent, Inc.

INN (שם בינלאומי):

EPINEPHRINE

הרכב:

EPINEPHRINE 1 mg in 1 mL

מסלול נתינה (של תרופות):

INTRAMUSCULAR

סוג מרשם:

PRESCRIPTION DRUG

סממני תרפויטית:

In general, the most common uses of epinephrine are to relieve respiratory distress due to bronchospasm, to provide rapid relief of hypersensitivity reactions to drugs and other allergens, and to prolong the action of infiltration anesthetics. Its cardiac effects may be of use in restoring cardiac rhythm in cardiac arrest due to various causes, but it is not used in cardiac failure or in hemorrhagic, traumatic, or cardiogenic shock. Epinephrine is used as a hemostatic agent. It is also used in treating mucosal congestion of hay fever, rhinitis and acute sinusitis; to relieve bronchial asthmatic paroxysms; in syncope due to complete heart block or carotid sinus hypersensitivity; for symptomatic relief of serum sickness, urticaria, angioneurotic edema; for resuscitation in cardiac arrest following anesthetic accidents; in simple (open angle) glaucoma; for relaxation of uterine musculature and to inhibit uterine contractions. Epinephrine injection can be utilized to prolong the action of local anesthetics (see C

leaflet_short:

Epinephrine Injection, USP 1:1000 (1 mg/mL) NDC 0517-1130-05                30 mL Multiple Dose Vial                  Boxes of 5 AMERICAN REGENT, INC. SHIRLEY, NY 11967 IN1130 Rev. 11/05

מצב אישור:

unapproved drug other

מאפייני מוצר

EPINEPHRINE - EPINEPHRINE INJECTION, SOLUTION
AMERICAN REGENT, INC.
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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EPINEPHRINE INJECTION, USP
1:1000
RX ONLY
DESCRIPTION
Epinephrine Injection, USP is a sterile, nonpyrogenic solution
intended for subcutaneous or
intramuscular injection. When diluted, it may also be administered
intracardially or intravenously. Each
mL contains: Epinephrine 1 mg (as the Hydrochloride), Water for
Injection q.s. Sodium Chloride added
for isotonicity, Chlorobutanol 0.5% (a chloroform derivative) as a
preservative and Sodium
Metabisulfite not more than 0.15% as an antioxidant. Epinephrine is
the active principle of the adrenal
medulla, chemically described as
(-)-3,4-Dihydroxy-α-[(methylamino)methyl)]benzyl alcohol, and has
the following structural formula:
CLINICAL PHARMACOLOGY
Epinephrine is a sympathomimetic drug. It activates an adrenergic
receptive mechanism on effector
cells and imitates all actions of the sympathetic nervous system
except those on the arteries of the face
and sweat glands. Epinephrine acts on both alpha and beta receptors
and is the most potent alpha receptor
activator.
INDICATIONS AND USAGE
In general, the most common uses of epinephrine are to relieve
respiratory distress due to
bronchospasm, to provide rapid relief of hypersensitivity reactions to
drugs and other allergens, and to
prolong the action of infiltration anesthetics. Its cardiac effects
may be of use in restoring cardiac
rhythm in cardiac arrest due to various causes, but it is not used in
cardiac failure or in hemorrhagic,
traumatic, or cardiogenic shock.
Epinephrine is used as a hemostatic agent. It is also used in treating
mucosal congestion of hay fever,
rhinitis and acute sinusitis; to relieve bronchial asthmatic
paroxysms; in syncope due to complete heart
block or carotid sinus hypersensitivity; for symptomatic relief of
serum sickness, urticari