DEXAMETHASONE tablet

מדינה: ארצות הברית

שפה: אנגלית

מקור: NLM (National Library of Medicine)

מרכיב פעיל:

DEXAMETHASONE (UNII: 7S5I7G3JQL) (DEXAMETHASONE - UNII:7S5I7G3JQL)

זמין מ:

Avera McKennan Hospital

INN (שם בינלאומי):

DEXAMETHASONE

הרכב:

DEXAMETHASONE 6 mg

סוג מרשם:

PRESCRIPTION DRUG

מצב אישור:

Abbreviated New Drug Application

מאפייני מוצר

DEXAMETHASONE- DEXAMETHASONE TABLET
AVERA MCKENNAN HOSPITAL
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DEXAMETHASONE TABLETS USP
DES CRIPTION
Dexamethasone Tablets USP are available for oral administration
containing either 0.5 mg, 0.75 mg, 1
mg, 1.5 mg, 2 mg, 4 mg or 6 mg of dexamethasone USP. Each tablet
contains the following inactive
ingredients: lactose monohydrate, magnesium stearate, starch, sugar,
D&C Yellow #10 (0.5 mg and 4
mg), FD&C Blue #1 (0.75 mg and 1.5 mg), FD&C Green #3 (4 mg and 6 mg),
FD&C Red #3 (1.5 mg),
FD&C Red #40 (1.5 mg), FD&C Yellow #6 (0.5 mg and 4 mg) and Yellow
Iron Oxide (1 mg).
Dexamethasone Oral Solution USP is formulated for oral administration
containing 0.5 mg per 5 mL of
dexamethasone USP. The cherry brandy flavored oral solution contains
the following inactive
ingredients: anhydrous citric acid, cherry brandy flavor, disodium
edetate, glycerin, methylparaben,
propylene glycol, propylparaben, sorbitol solution and water.
Dexamethasone Oral Solution USP Intensol™ (Concentrate) is
formulated for oral administration
containing 1 mg per mL of dexamethasone USP. In addition, the oral
solution contains the following
inactive ingredients: alcohol 30% v/v, anhydrous citric acid, benzoic
acid, disodium edetate, propylene
glycol and water.
Dexamethasone, a synthetic adrenocortical steroid, is a white to
practically white, odorless, crystalline
powder. It is stable in air. It is practically insoluble in water. The
molecular formula is C
H FO .
The molecular weight is 392.47. It is designated chemically as
9-fluoro-11β,17,21-trihydroxy-16α-
methylpregna-1,4-diene,3,20-dione and the structural formula is:
CLINICAL PHARMACOLOGY
Glucocorticoids, naturally occurring and synthetic, are adrenocortical
steroids that are readily absorbed
from the gastrointestinal tract. Glucocorticoids cause varied
metabolic effects. In addition, they modify
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the body's immune responses to diverse stimuli. Naturally occurring
glucocorticoids (hydrocortisone
and cortisone), which also have sodium-retaining properties, are used
as repl