CLIMARA 25 PATCH

מדינה: קנדה

שפה: אנגלית

מקור: Health Canada

מרכיב פעיל:

ESTRADIOL (ESTRADIOL HEMIHYDRATE)

זמין מ:

BAYER INC

קוד ATC:

G03CA03

INN (שם בינלאומי):

ESTRADIOL

כמות:

25MCG

טופס פרצבטיות:

PATCH

הרכב:

ESTRADIOL (ESTRADIOL HEMIHYDRATE) 25MCG

מסלול נתינה (של תרופות):

TRANSDERMAL

יחידות באריזה:

4

סוג מרשם:

Prescription

איזור תרפויטי:

ESTROGENS

leaflet_short:

Active ingredient group (AIG) number: 0106457033; AHFS:

מצב אישור:

APPROVED

תאריך אישור:

2007-03-08

מאפייני מוצר

17β)
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John’s wort.
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17β. Upon application to
17β, the major estrogenic hormone secreted by the human ovary.
17β is the predominant estrogen produced by the ovaries in
premenopausal women.
17β), and provides controlled delivery of estradiol
17β,
17β), and provides controlled delivery of estradiol
17β, 0.05
17β), and provides controlled delivery of estradiol
17β,
17β)
PART II: SCIENTIFIC INFORMATION
β
2 •
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17β per day) is not approved for
completed the study. Both CLIMARA 50 and CLIMARA 100 were
significantly (p ≤ 0.05) more
efficacy parameters. Statistically significant (p ≤ 0.05) treatment
effects with both doses were
–
change from baseline significantly (p≤0.05) less for placebo group
than for the CLIMARA 50 and CLIMARA 100
Mean score significantly (p≤0.05) less for the placebo group than
for the CLIMARA 50 and CLIMARA 100
CLIMARA 50 and CLIMARA 100 statistically significant at p ≤ 0.05.
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Mean score significantly (p ≤ 0.05) less for the for the CLIMARA 50
group than for the CLIMARA 100
Mean score significantly (p ≤ 0.05) less for the for the CLIMARA 50
group than for the CLIMARA 100 group, and, mean score
significantly (p ≤ 10.05) less for the
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Patient’s Assessment
Investigator’s Assessment
Patient’s Assessment
Investigator’s Assessment
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<0.0001‡
<0.0001 ‡
0.0001 ‡
<0.0001‡
<0.0001 ‡
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‡ p < 0.05
17β per day) is not approved for sale in Canada.
–
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0.0141 ‡
<0.0001 ‡
0.0001 ‡
<0.0001 ‡
<0.0001 ‡
†
‡ p < 0.05
17β per day) is not approved for sale in Canada.
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crease in bone mineral density at the hip (trochanteric region,
Ward’s triangle, femoral neck) and spine
Ward’s Triang