מדינה: הממלכה המאוחדת
שפה: אנגלית
מקור: MHRA (Medicines & Healthcare Products Regulatory Agency)
Chlorpromazine hydrochloride
Thornton & Ross Ltd
N05AA01
Chlorpromazine hydrochloride
25mg
Oral tablet
Oral
No Controlled Drug Status
Valid as a prescribable product
BNF: 04020100
IN THIS LEAFLET: 1. What Chlorpromazine is and what it is used for 2. Before you take Chlorpromazine tablets 3. How to take Chlorpromazine tablets 4. Possible side effects 5. How to store Chlorpromazine tablets 6. Further information 1. WHAT CHLORPROMAZINE IS AND WHAT IT IS USED FOR Chlorpromazine belongs to a group of drugs known as antipsychotics, which act on the central nervous system. CHLORPROMAZINE TABLETS ARE USED FOR: − The treatment of behavioural disturbances, including schizophrenia, mania and hypomania − The short-term treatment of anxiety, agitation and violent or impulsive behaviour − The treatment of persistent hiccup and nausea and vomiting associated with terminal illness. 2. BEFORE YOU TAKE CHLORPROMAZINE TABLETS DO NOT TAKE CHLORPROMAZINE TABLETS IF YOU: – Are allergic (hypersensitive) to - Chlorpromazine - Any of the other ingredients of Chlorpromazine tablets (see section 6 “Further information”) – Have a low blood cell count (bone marrow depression) CHECK WITH YOUR DOCTOR BEFORE TAKING CHLORPROMAZINE TABLETS IF YOU: − Suffer from liver or kidney problems – Suffer from epilepsy (fits) – Have had, or any member of your family has had, any disease that has affected the heart or blood circulation – Or someone else in your family has a history of blood clots, as medicines like this have been associated with formation of blood clots – Have an underactive thyroid gland (hypothyroidism) – Suffer from a physical disorder of the brain that causes decreased mental function, such as Parkinson’s disease – Have a tumour of your adrenal gland – Suffer from the condition myasthenia gravis (muscular weakness) – Have prostate trouble – Have had glaucoma (painful eyes with blurred vision) – Suffer from any metabolic disorder such as low levels of calcium, magnesium or potassium in the blood – Suffer from dehydration or have recently lost a lot of blood. If you are to undergo SURGERY you should inform the surgeon and anaesthetist of your treatment with Chlorpromazine as t קרא את המסמך השלם
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE MEDICINAL PRODUCT Chlorpromazine Tablets BP 25 mg 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Chlorpromazine Hydrochloride BP 25 mg 3 PHARMACEUTICAL FORM Sugar Coated Tablets 4 CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Chlorpromazine is a phenothiazine neuroleptic and is indicated in the following conditions. 1. Psychotic conditions (especially paranoid) including schizophrenia, mania and hypomania. 2. As an adjunct in the short term management of anxiety psychomotor agitation excitement, violent or dangerously impulsive behaviour. 3. Nausea or vomiting associated with terminal illness, where other agents are ineffective or unavailable. 4. Induction of hypothermia to prevent shivering and cause vasolidation. 5. Intractable hiccup. 6. Childhood schizophrenia and autism. 4.2 POSOLOGY AND METHOD OF ADMINISTRATION Method of Administration: Tablets are to be taken orally with a drink of water. Posology: Dosage: Dosage varies both with the individual and with the purpose for which the drug is being used. The dosage should be low to begin with and increased, gradually, under close supervision until the optimum level of control is achieved. Dosage in Schizophrenia, Other Psychoses Anxiety and Agitation etc: Adults: Initially 25mg three times daily or 75mg at bedtime, increasing by daily amounts of 25mg to the effective maintenance dose. The usual maintenance dose is in the range of 75 to 300mg daily, although some patients may require up to 1.0g daily. Children: (i) Aged under 1 year: Chlorpromazine should generally not be used unless the need is life-saving. (ii) Age 1 to 5 years: 0.5mg/kg every 4 to 6 hours to a maximum daily dosage of 40mg. (ii) Age 6 to 12 years: One-third to half the adult dose to a maximum daily dosage of 75mg. Elderly or Debilitated Patients: Initially one-third to half the usual adult dose with a more gradual increase in dosage. Dosage in Hiccup: Adults: 25-50mg three to four times daily Children: No information available. Elderly: One-third קרא את המסמך השלם