Mucorid-P Syrup

Maa: Malesia

Kieli: englanti

Lähde: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktiivinen ainesosa:

PROMETHAZINE HYDROCHLORIDE; Carbocisteine

Saatavilla:

STERILINE SDN. BHD.

INN (Kansainvälinen yleisnimi):

PROMETHAZINE HYDROCHLORIDE; Carbocisteine

Kpl paketissa:

60ml mL; 90ml mL; 120ml mL

Valmistaja:

Noripharma Sdn. Bhd.

Valmisteyhteenveto

MUCORID-P SYRUP
COMPOSITION:
Each 5ml contains Carbocisteine 100mg, Promethazine Hydrochloride
2.5mg and
Methylparaben (as preservative) 7.5mg.
DESCRIPTION:
A brown colored syrup having fruity flavor.
PHARMACODYNAMIC:
Carbocisteine is a mucolytic agent which decreases the pathological
viscosity of the
mucus, fluidifies it and facilitates its evacuation, thus promoting
recovery. As a
mucoregulatory agent, it helps generate the impaired mucosa.
Promethazine is a long acting antihistamine with a mild atropine-like
anticholinergic effect
and because of its marked effect on the central nervous system, is of
great value as an
antiemetic, hypnotic, tranquilizer, a potentiator of anaesthetic,
hypnotics, sedatives and
analgesics.
PHARMACOKINETIC:
Carbocisteine is rapidly and well absorbed from the gastrointestinal
tract with peak plasma
concentrations occurring 90 to 120 minutes after an oral dose. It
appears to penetrate into
lung tissue and respiratory mucus.
Carbocisteine is excreted in the urine as unchanged drug and
metabolites. Acetylation,
decarboxylation and sulfoxidation have been identified as the major
metabolic pathways.
Sulfoxidation may be governed by genetic polymorphism.
Promethazine is well absorbed from the gastrointestinal tract.
Clinical effects are apparent
within 20 minutes after oral administration and generally last four to
six hours, although
they may persist as long as 12 hours. Promethazine is metabolized by
the liver to a
variety of compounds; the sulfoxides of promethazine and
N-demethylpromethazine are
the predominant metabolites appearing in the urine.
INDICATION:
Symptomatic treatment of troublesome, non-productive cough,
particularly occurring at
night.
RECOMMENDED DOSAGE:
For adults and children over the age of 2 years only.
Symptomatic treatment should be for a short period (a few days) and
restricted when
cough occurs.
Adults: 3 to 4 tablespoonfuls (15ml) daily.
Children:
24 to 30 months: 15 - 20ml per day
30 months to 12 years: 20 - 30ml per day
12 to 15 years: 30 - 45ml per day
Becaus