Maa: Yhdysvallat
Kieli: englanti
Lähde: NLM (National Library of Medicine)
CHORIONIC GONADOTROPIN (UNII: 20ED16GHEB) (CHORIONIC GONADOTROPIN - UNII:20ED16GHEB)
Merck Sharp & Dohme Corp.
Gonadotrophin, Chorionic
Gonadotrophin, Chorionic 10000 [iU]
PRESCRIPTION
INDICATIONS COWS: CHORULON® is indicated for intramuscular use in cows for the treatment of nymphomania (frequent or constant heat) due to cystic ovaries. FINFISH: CHORULON® is indicated for use as an aid in improving spawning function in male and female brood finfish.
HOW SUPPLIED CHORULON® is supplied in cartons containing five vials of freeze-dried powder and five 10 mL vials of sterile diluent. order Code No. CH-475-1.
New Animal Drug Application
CHORULON- GONADOTROPHIN, CHORIONIC MERCK SHARP & DOHME CORP. ---------- CHORULON Approved by FDA under NADA # 140-927 FOR ANIMAL USE ONLY CAUTION Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION CHORULON is a freeze-dried preparation of chorionic gonadotropin (human Chorionic Gonadotropin or hCG) for intramuscular administration after reconstitution. When reconstituted with the accompanying sterile diluent, each 10 mL vial contains 10,000 I.U. chorionic gonadotropin (equivalent to 10,000 USP Units chorionic gonadotropin) and 10 mg mannitol, with mono- and disodium phosphate to adjust the pH of the solution. ACTION Chorionic gonadotropin has luteinizing hormone-like activity with little or no follicle stimulating or estrogenic activity. INDICATIONS COWS: CHORULON is indicated for intramuscular use in cows for the treatment of nymphomania (frequent or constant heat) due to cystic ovaries. FINFISH: CHORULON is indicated for use as an aid in improving spawning function in male and female brood finfish. DOSAGE AND ADMINISTRATION To reconstitute, transfer the contents of one vial of sterile diluent into one vial of freeze- dried powder. The resulting 10 mL of CHORULON contains 10,000 I.U. chorionic gonadotropin. COWS: The contents of one vial (10 mL) of reconstituted CHORULON should be administered as a single deep intramuscular injection. Dosage may be repeated in 14 days if the animal's behavior or rectal examination of the ovaries indicates the necessity for retreatment. FINFISH: CHORULON should be administered via intramuscular injection just ventral to the dorsal fin for one (1) to three (3) injections. Any single injection should be administered, depending on the fish species, at a dose of 50 to 510 I.U./lb body weight (bw) for males and 67 to 1816 I.U./lb bw for females. Depending on body weight and dose administered, it may be necessary to divide the dose among two or more injection sites to avoid injecting a large volume at a single site. Summaries of doses test Lue koko asiakirja