Riik: Austraalia
keel: inglise
Allikas: Department of Health (Therapeutic Goods Administration)
Lignocaine hydrochloride
Specialites Septodont Pty Ltd
Medicine Registered
LIGNOCAINE INJECTION CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Lignocaine Injection. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking Lignocaine Injection against the benefits this medicine is expected to have for you. This medicine is likely to be used while you are at the clinic or in hospital. If possible, please read this leaflet carefully before this medicine is given to you. In some cases this leaflet may be given to you after the medicine has been used. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET. You may need to read it again. WHAT LIGNOCAINE INJECTION IS USED FOR Lignocaine Injection belongs to two groups of medicines known as local anaesthetics and antiarrhythmic drugs. Local anaesthetics stop pain and feeling in the area around where it is injected; and antiarrhythmic drugs work by restoring irregular and/or rapid heart beats to normal. Lignocaine Injection may be used for the management of other conditions that are not mentioned above. Your doctor will be able to tell you about the specific condition for which you have been prescribed Lignocaine Injection. This medicine is available only with a doctor's prescription. BEFORE YOU ARE GIVEN LIGNOCAINE INJECTION _WHEN YOU MUST NOT BE GIVEN_ _IT_ DO NOT USE LIGNOCAINE INJECTION IF: • you have an allergy to lignocaine or any of the ingredients listed at the end of this leaflet. Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing, swelling of the face, lips, tongue or other parts of the body, rash, itching or hives on the skin. • you have an infection or swelling where the injection will be given • you have blood infections or disorders • you are in severe shock • you have low blood pressure • you have diseases of Lugege kogu dokumenti
Product Information LIGNOCAINE INJECTION Page 1 of 10 Version: pfpligni10511 Supersedes: pfpligni 10410 NAME OF DRUG Lignocaine Hydrochloride. DESCRIPTION Lignocaine hydrochloride is 2-diethylamino- 2',6'- dimethylacetanilide hydrochloride monohydrate. It appears as a white, crystalline powder that is very soluble in water, freely soluble in alcohol and practically insoluble in ether. The structural formula is represented below. (H 5 C 2 ) 2 N CH 2 C NH H 3 C H 3 C O , HCl, H 2 O Molecular Formula: C 14 H 22 N 2 O,HCl,H 2 O Molecular Weight: 288.8 CAS Number: 6108-05-0 Lignocaine Injection is a clear, colourless, sterile, isotonic, preservative-free solution containing Lignocaine Hydrochloride BP 1% or 2% and Sodium Chloride BP in Water for Injections BP. PHARMACOLOGY CLASS: Local anaesthetic of the amide type and antiarrhythmic drug. MECHANISM OF ACTION: Lignocaine stabilises all potentially excitable membranes and prevents the initiation and transmission of nerve impulses. This produces a local anaesthetic effect. Onset of action is rapid and blockade may last from 60 - 90 minutes. Studies of the effects of therapeutic concentrations of lignocaine on the electrophysiological properties of mammalian Purkinje fibers have shown that lignocaine attenuates phase 4 diastolic depolarisation, decreases automaticity, and causes a decrease or no change in excitability and membrane responsiveness. Action potential duration and effective refractory period of Purkinje fibers are decreased, while the ratio of effective refractory period to action potential duration Lugege kogu dokumenti