Riik: Malaisia
keel: inglise
Allikas: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
DEXAMETHASONE
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
DEXAMETHASONE
1000 Tablet Tablets
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ 1 DEXALONE TABLET Dexamethasone (0.5mg, 0.75mg) WHAT IS IN THIS LEAFLET 1. What Dexalone Tablet is used for 2. How Dexalone Tablet works 3. Before you use Dexalone Tablet 4. How to use Dexalone Tablet 5. While you are using it 6. Side effects 7. Storage and Disposal of Dexalone Tablet 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT DEXALONE TABLET IS USED FOR Dexamethasone can be used to: • reduce inflammation • treat a number of different diseases of the immune system Please refer to the doctor for more information. HOW DEXALONE TABLET WORKS Dexalone Tablet contains dexamethasone. This belongs to a group of medicines called corticosteroids. Corticosteroids work by reducing inflammation. BEFORE YOU START TO USE DEXALONE TABLET - _When you must not use it _ Do not take this medicine: • after the expiry date printed on the pack • if the packaging is torn or shows signs of tampering. • if you are allergic (hypersensitive) to dexamethasone or any other ingredients in this medicine. The signs of an allergic reaction include a rash, itching or shortness of breath • if you have an infection • if you have taken vaccination recently If you are not sure whether you should start taking it, talk to your doctor or pharmacist. Doctor will prepare a few test or examination for you e.g. blood test, urine test, stool test, eye examination, growth and development for children and adolescent. _Pregnancy and lactation _ Do not take Dexalone Tablet if you are pregnant, trying to get pregnant or think you may be pregnant. Do not take Dexalone Tablet if you are breast-feeding. Ask your doctor or pharmacist for advice before taking any medicine. Dexamethasone may be found in breast milk and may cause unwanted effects. - _Before you start to use it _ _Tell your doctor if you have: _ • Acquired Immunodeficiency Syndrome (AIDS) or Human Immunodeficiency Virus (HIV) • Recent intestinal surgery • Heart diseases • High blo Lugege kogu dokumenti
Dexalone Tablet 0.5 A 6.5 mm diameter, round, flat, scored, white tablet. _Each tablet contains Dexamethasone 0.5 mg_ Dexalone Tablet 0.75 An oval shape, scored, white tablet. _Each tablet contains Dexamethasone 0.75 mg_ INDICATIONS Dexamethasone is indicated for treatment of adrenocortical function abnormalities, allergic disorders, collagen disorders, dermatologic disorders, gastrointestinal disorders, haematologic disorders, prophylaxis of cancer chemotherapy-induced nausea and vomiting, hypercalcaemia associated with neoplasms, nonrheumatic inflammation, neoplastic disease, neurologic disease, neurotrauma, ophthalmic disorders, oral disorders, pericarditis, nasal polyps, respiratory disorders, rheumatic disorders, nonsuppurative thyroiditis, organ transplant rejection and trichinosis. Dexamethasone is also indicated in the diagnosis of Cushing's syndrome and to distinguish Cushing's syndrome caused by excessive corticotropin secretion from that due to other causes and diagnosis and evaluation of the efficacy of treatment in endogenous depression. PHARMACODYNAMICS Dexamethasone diffuses across cell membranes and complex with specific cytoplasmic receptors which then enter the cell nucleus, bind to DNA, and stimulate transcription of messenger RNA (mRNA) and subsequently protein synthesis of various enzymes thought to be ultimately responsible for glucocorticoid effects of systemic corticosteroids. Dexamethasone decreases or prevents tissue responses to inflammatory processes, thereby reducing development of symptoms of inflammation without affecting the underlying cause. Dexamethasone inhibits accumulation of inflammatory cells, including macrophages and leukocytes, at sites of inflammation. It also inhibits phagocytosis, lysosomal enzyme release, and synthesis and/or release of several chemical mediators of inflammation. Although the exact mechanisms are not completely understood, actions that contribute significantly to these effects include blockade of the action of macrophage inhibitory factor (MIF), leadi Lugege kogu dokumenti