DEXALONE TABLET 0.5

Страна: Малайзия

Език: английски

Източник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активна съставка:

DEXAMETHASONE

Предлага се от:

DUOPHARMA MANUFACTURING (BANGI) SDN BHD

INN (Международно Name):

DEXAMETHASONE

Броя в опаковка:

1000 Tablet Tablets

Произведено от:

DUOPHARMA MANUFACTURING (BANGI) SDN BHD

Листовка

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
1
DEXALONE TABLET
Dexamethasone (0.5mg, 0.75mg)
WHAT IS IN THIS LEAFLET
1.
What Dexalone Tablet is
used for
2.
How
Dexalone
Tablet
works
3.
Before you use Dexalone
Tablet
4.
How to use Dexalone
Tablet
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of
Dexalone Tablet
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
WHAT DEXALONE TABLET IS
USED FOR
Dexamethasone can be used to:
•
reduce inflammation
•
treat a number of different
diseases of the immune system
Please refer to the doctor for
more information.
HOW DEXALONE TABLET WORKS
Dexalone
Tablet
contains
dexamethasone. This belongs
to a group of medicines called
corticosteroids. Corticosteroids
work
by
reducing
inflammation.
BEFORE
YOU
START
TO
USE
DEXALONE TABLET
-
_When you must not use it _
Do not take this medicine:
•
after
the
expiry
date
printed on the pack
•
if the packaging is torn or
shows signs of tampering.
•
if
you
are
allergic
(hypersensitive)
to
dexamethasone
or
any
other
ingredients
in
this
medicine. The signs of an
allergic reaction include a
rash, itching or shortness
of breath
•
if you have an infection
•
if
you
have
taken
vaccination recently
If you are not sure whether you
should start taking it, talk to your
doctor or pharmacist.
Doctor will prepare a few test
or
examination
for
you
e.g.
blood test, urine test, stool test,
eye
examination,
growth
and
development for children and
adolescent.
_Pregnancy and lactation _
Do not take Dexalone Tablet if
you are pregnant, trying to get
pregnant or think you may be
pregnant.
Do not take Dexalone Tablet if
you
are
breast-feeding.
Ask
your doctor or pharmacist for
advice
before
taking
any
medicine.
Dexamethasone may be found
in breast milk and may cause
unwanted effects.
-
_Before you start to use it _
_Tell your doctor if you have: _
•
Acquired
Immunodeficiency
Syndrome
(AIDS)
or
Human Immunodeficiency
Virus (HIV)
•
Recent intestinal surgery
•
Heart diseases
•
High blo

Данни за продукта

Dexalone Tablet 0.5
A 6.5 mm diameter, round, flat, scored, white tablet.
_Each tablet contains Dexamethasone 0.5 mg_
Dexalone Tablet 0.75
An oval shape, scored, white tablet.
_Each tablet contains Dexamethasone 0.75 mg_
INDICATIONS
Dexamethasone is indicated for treatment of adrenocortical function
abnormalities,
allergic
disorders,
collagen
disorders,
dermatologic
disorders,
gastrointestinal
disorders, haematologic disorders, prophylaxis of cancer
chemotherapy-induced
nausea and vomiting, hypercalcaemia associated with neoplasms,
nonrheumatic
inflammation, neoplastic disease, neurologic disease, neurotrauma,
ophthalmic
disorders, oral disorders, pericarditis, nasal polyps, respiratory
disorders, rheumatic
disorders, nonsuppurative thyroiditis, organ transplant rejection and
trichinosis.
Dexamethasone is also indicated in the diagnosis of Cushing's syndrome
and to
distinguish Cushing's syndrome caused by excessive corticotropin
secretion from
that due to other causes and diagnosis and evaluation of the efficacy
of treatment in
endogenous depression.
PHARMACODYNAMICS
Dexamethasone
diffuses
across
cell
membranes
and
complex
with
specific
cytoplasmic receptors which then enter the cell nucleus, bind to DNA,
and stimulate
transcription of messenger RNA (mRNA) and subsequently protein
synthesis of
various enzymes thought to be ultimately responsible for
glucocorticoid effects of
systemic corticosteroids.
Dexamethasone
decreases
or
prevents
tissue
responses
to
inflammatory
processes, thereby reducing development of symptoms of inflammation
without
affecting
the
underlying
cause.
Dexamethasone
inhibits
accumulation
of
inflammatory cells, including macrophages and leukocytes, at sites of
inflammation.
It also inhibits phagocytosis, lysosomal enzyme release, and synthesis
and/or
release
of
several
chemical
mediators
of
inflammation. Although
the
exact
mechanisms are not completely understood, actions that contribute
significantly to
these effects include blockade of the action of macrophage inhibitory
factor (MIF),
leadi