Salbutamol Inhalation Solution

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Salbutamol

Available from:

Pfizer Australia Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

SALBUTAMOL
INHALATION
SOLUTION

CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Salbutamol
Inhalation Solution. It does not
contain all the available information.
It does not take the place of talking to
your doctor or pharmacist.
All medicines have benefits and
risks. Your doctor has weighed the
risks of you taking Salbutamol
Inhalation Solution against the
benefits this medicine is expected to
have for you.
This medicine is likely to be used
while you are at the clinic or in
hospital. If possible, please read this
leaflet carefully before this medicine
is given to you. In some cases this
leaflet may be given to you after the
medicine has been used.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET.
You may need to read it again.
WHAT SALBUTAMOL
INHALATION SOLUTION IS
USED FOR
Salbutamol Inhalation Solution
belongs to a group of medicines
called beta-2-agonists. These work
rapidly to open up the air passages in
your lungs.
Salbutamol is inhaled into the lungs
for the treatment of asthma. Asthma
is a disease where the lining of the
lungs become inflamed (red and
swollen), making it difficult to
breathe. This may be due to an
allergy to house dust mites, smoke,
air-borne pollution and other
irritants. Salbutamol opens up the air
passages in people suffering from
asthma, bronchitis and other
breathing problems. It may also be
used before exercise to keep your air
passages open if you start to wheeze
or have difficulty breathing each time
you exert yourself.
Salbutamol Inhalation Solution may
be used for the management of other
conditions that are not mentioned
above. Your doctor will be able to
tell you about the specific condition
for which you have been prescribed
Salbutamol Inhalation Solution.
This medicine is available only with
a doctor's prescription.
BEFORE YOU USE
SALBUTAMOL INHALATION
SOLUTION
_WHEN YOU MUST NOT BE GIVEN_
_IT_
DO NOT USE SALBUTAMOL INHALATION
SOLUTION IF YOU HAVE AN AL

Summary of Product characteristics

Version: pfpsalbj10312 
Supersedes: pfpsalbu10112 

Page 1 of 9 
PRODUCT INFORMATION 
SALBUTAMOL INHALATION SOLUTION 
(SALBUTAMOL SULFATE) 
NAME OF THE MEDICINE 
Salbutamol
sulfate is di[(_RS_)-2-(1,1-dimethyl)ethylamino-1-[4-hydroxy-3 
-
(hydroxymethyl)phenyl]ethanol] sulfate.  It
is a white or almost white, crystalline, odourless 
powder with a slightly bitter taste.  It
is freely soluble in water, slightly soluble in alcohol and 
in ether, very slightly soluble in methylene chloride.
 Salbutamol sulfate 1.2  mg is 
approximately equivalent to 1 mg of salbutamol. 
The structural formula is represented below
. 

Molecular Formula: 
(C
13
H
21
NO
3
)
2
,H
2
SO
4

Molecular Weight: 
576.7 
CAS Number: 
51022-70-9 
DESCRIPTION 
Salbutamol Inhalation Solution in
bottles is a clear nebuliser solution containing salbutamol 
0.5%w/v (5  mg/mL) as Salbutamol Sulfate and
benzalkonium chloride as preservative and 
Water for Injections. 
Salbutamol Inhalation Solution Sterinebs is a clear, isotonic,
preservative-free nebuliser 
solution for single use.
 Sterinebs contain either  salbutamol 2.5  mg
or 5  mg as Salbutamol 
Sulfate and sodium chloride and Water for Injections to
2.5 mL. 
Version: pfpsalbj10312 
Supersedes: pfpsalbu10112 

Page 2 of 9 
PHARMACOLOGY 
CLASS OF DRUG 
Selective beta-2 adrenoceptor agonist. 
MODE OF ACTION 
Salbutamol
is a long acting, relatively selective beta-2-receptor stimulant. 
Administration by 
inhalation results in direct stimulation of beta-2-receptors in
bronchial smooth muscle and 
hence bronchodilation.  This is thought to be due to
stimulation  of adenyl cyclase by 
salbutamol, resulting in increased levels of cyclic AMP within cells. 
These are thought to 
inhibit the entry of calcium ions into the cells,
thus inhibiting smooth muscle contraction.  
High levels of cycli