Země: Austrálie
Jazyk: angličtina
Zdroj: Department of Health (Therapeutic Goods Administration)
Salbutamol
Pfizer Australia Pty Ltd
Medicine Registered
SALBUTAMOL INHALATION SOLUTION CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Salbutamol Inhalation Solution. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking Salbutamol Inhalation Solution against the benefits this medicine is expected to have for you. This medicine is likely to be used while you are at the clinic or in hospital. If possible, please read this leaflet carefully before this medicine is given to you. In some cases this leaflet may be given to you after the medicine has been used. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET. You may need to read it again. WHAT SALBUTAMOL INHALATION SOLUTION IS USED FOR Salbutamol Inhalation Solution belongs to a group of medicines called beta-2-agonists. These work rapidly to open up the air passages in your lungs. Salbutamol is inhaled into the lungs for the treatment of asthma. Asthma is a disease where the lining of the lungs become inflamed (red and swollen), making it difficult to breathe. This may be due to an allergy to house dust mites, smoke, air-borne pollution and other irritants. Salbutamol opens up the air passages in people suffering from asthma, bronchitis and other breathing problems. It may also be used before exercise to keep your air passages open if you start to wheeze or have difficulty breathing each time you exert yourself. Salbutamol Inhalation Solution may be used for the management of other conditions that are not mentioned above. Your doctor will be able to tell you about the specific condition for which you have been prescribed Salbutamol Inhalation Solution. This medicine is available only with a doctor's prescription. BEFORE YOU USE SALBUTAMOL INHALATION SOLUTION _WHEN YOU MUST NOT BE GIVEN_ _IT_ DO NOT USE SALBUTAMOL INHALATION SOLUTION IF YOU HAVE AN AL Přečtěte si celý dokument
Version: pfpsalbj10312 Supersedes: pfpsalbu10112 Page 1 of 9 PRODUCT INFORMATION SALBUTAMOL INHALATION SOLUTION (SALBUTAMOL SULFATE) NAME OF THE MEDICINE Salbutamol sulfate is di[(_RS_)-2-(1,1-dimethyl)ethylamino-1-[4-hydroxy-3 - (hydroxymethyl)phenyl]ethanol] sulfate. It is a white or almost white, crystalline, odourless powder with a slightly bitter taste. It is freely soluble in water, slightly soluble in alcohol and in ether, very slightly soluble in methylene chloride. Salbutamol sulfate 1.2 mg is approximately equivalent to 1 mg of salbutamol. The structural formula is represented below . Molecular Formula: (C 13 H 21 NO 3 ) 2 ,H 2 SO 4 Molecular Weight: 576.7 CAS Number: 51022-70-9 DESCRIPTION Salbutamol Inhalation Solution in bottles is a clear nebuliser solution containing salbutamol 0.5%w/v (5 mg/mL) as Salbutamol Sulfate and benzalkonium chloride as preservative and Water for Injections. Salbutamol Inhalation Solution Sterinebs is a clear, isotonic, preservative-free nebuliser solution for single use. Sterinebs contain either salbutamol 2.5 mg or 5 mg as Salbutamol Sulfate and sodium chloride and Water for Injections to 2.5 mL. Version: pfpsalbj10312 Supersedes: pfpsalbu10112 Page 2 of 9 PHARMACOLOGY CLASS OF DRUG Selective beta-2 adrenoceptor agonist. MODE OF ACTION Salbutamol is a long acting, relatively selective beta-2-receptor stimulant. Administration by inhalation results in direct stimulation of beta-2-receptors in bronchial smooth muscle and hence bronchodilation. This is thought to be due to stimulation of adenyl cyclase by salbutamol, resulting in increased levels of cyclic AMP within cells. These are thought to inhibit the entry of calcium ions into the cells, thus inhibiting smooth muscle contraction. High levels of cycli Přečtěte si celý dokument