Oxitetraciclin 200LA

Country: Armenia

Language: English

Source: Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում

Active ingredient:

oxytetracycline

Available from:

Invesa Industrial Veterinaria

INN (International Name):

oxytetracycline

Dosage:

200mg/ml

Pharmaceutical form:

solution for injection

Prescription type:

Prescription

Summary of Product characteristics

OXITETRACICLINA 200 L.A. PART 1
Oxytetracycline Injectable solution
_ _
PART 1
SUMMARY OF PRODUCT
CHARACTERISTICS, LABELLING AND
LEAFLET
OXITETRACICLINA 200 L.A. PART 1
Oxytetracycline Injectable solution
_ _
SUMMARY OF PRODUCT CHARACTERISTICS
1.- NAME OF THE VETERINARY MEDICINAL PRODUCT
OXITETRACICLINA 200 L.A.
2. QUALITATIVE AND QUANTITATIVE COMPOSITION
Oxytetracycline (dihydrate)
200 mg
Magnesium chloride hexahydrate
100 mg
Monoethanolamine
67.5
µ
l
2-pyrrolidone
0.4 ml
Sodium formaldehyde sulfoxylate
2 mg
Polyvinylpyrrolidone
50 mg
Water for injection q.s.
1 ml
3. PHARMACEUTICAL FORM
SOLUTION FOR INJECTION
4. PHARMACOLOGYCAL PROPERTIES
Pharmacotherapeutical group: Antibacterials for systemic use.
ATCvet code: QJ01AA06
OXITETRACICLINA 200 L.A. PART 1
Oxytetracycline Injectable solution
_ _
4.1. PHARMACODYNAMIC PROPERTIES
Oxytetracycline is a bacteriostatic antibiotic that acts on bacterial
ribosomes by
inhibiting the protein synthesis. It has a very broad spectrum of
activity, which includes
gram positive germs, gram negative germs, some big viruses, protozoa,
spirochaetes,
rickettsias, mycoplasmas and chlamydias.
Thanks to its long-acting formula, a single injection of
OXITETRACICLINA 200 L.A.
can reach a complete antibiotherapy, due to the fact that efficacious
blood levels are
maintained for 3 days.
4.2. PHARMACOKINETIC PROPERTIES
After intramuscular administration, plasmatic concentrations of
oxytetracycline are
detectable during the first 30 minutes, and thanks to its long-action
formulation it
mantains significant blood concentrations for 3 days.
Once absorbed, it binds to plasmatic proteins. It is distributed in
all the organism
specially in lung, kidney, liver and spleen where the highest
concentrations are
reached as well as in active zones of ossification. It presents lower
concentrations in
saliva, ocular humours and milk. It also crosses placental barrier.
Tetracyclines diffuse with difficulty to the cerebrospinal liquid,
being in a higher degree
when meninges are inflammed.
It is excreted mainly