LSTYVET 50%WW PREMIX POWDER

Country: Malaysia

Language: English

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Active ingredient:

TYLOSIN PHOSPHATE

Available from:

Lim Seng Pharmachem Sdn Bhd

INN (International Name):

TYLOSIN PHOSPHATE

Units in package:

1 kg

Manufactured by:

Thye Pharma Sdn. Bhd

Summary of Product characteristics

Veterinary Package Insert
LSTYVET
50%
W/W
PREMIX
POWDER
(50% Tylosin Phosphate)
PRODUCT DESCRIPTION
White to pale yellow colour powder, which contains
500mg of tylosin phosphate per gram.
PHARMACODYNAMICS & PHARMACOKINETICS
Tylosin
has
the
same
mechanism
of
antibiotic
action as other macrolides, that is, binding to the
50S
ribosome
fraction,
resulting
in
inhibition
of
protein
synthesis. Tylosin
has
a
dominant
bacteriostatic activity.
Tylosin
is
widely
distributed
in
the
body
after
absorption
but
does
not
cross
the
blood-brain
barrier. It is eliminated by the urinary tract and bile
unchanged. The half-life of elimination of tylosin is
of the order of one to two hours depending on the
animal species.
INDICATION
For tylosin-sensitive diseases in poultry and pigs.
Poultry:
Prevention
in
an
infected
environment
and
treatment of avian mycoplasmosis.
Chickens:
Prevention in infected medium of necrotic enteritis
due to Clostridium perfringens.
Pigs:
Prevention
in
an
infected
environment
of
haemorrhagic enteritis.
Prevention
in
infected
environment
of
enzootic
pneumonia.
TARGET SPECIES
Poultry, chickens and pigs.
RECOMMENDED DOSAGE AND ADMINISTRATION
In poultry:
Prevention in infected medium and treatment of
avian mycoplasmosis:
50 to 100 mg of tylosin (110.7 to 221.4mg of
product) per kg of live weight and per day orally for
2 to 5 days.
For a daily dietary intake of 100 g of feed per kg of
live weight, this dosage corresponds to 500 to 1000
ppm of tylosin in the feed, ie an incorporation rate of
11.07 kg to 22.14 kg
of medicated premix per ton
of feed.
In chickens:
Prevention in infected medium of necrotic enteritis
due to Clostridium perfringens:
10 to 20 mg of tylosin (22.1 to 44.3mg of product)
per kg of live weight and per day orally for 7 days.
For a daily dietary intake of 100 g of feed per kg of
live weight, this dosage corresponds to 100 ppm to
200 ppm of tylosin in the feed, ie an incorporation
rate of 2.21kg to 4.43kg of medicated premix per
ton of food.
In pigs:
Prevention
in
an
infected
environment
of
haemor