LEUKERIN POWDER 10% (ロイケリン散10％)

Country: Japan

Language: English

Source: すりの適正使用協議会 RAD-AR Council, Japan

Active ingredient:

Mercaptopurine

Available from:

OHARA Pharmaceutical Co.,Ltd.

INN (International Name):

Mercaptopurine

Pharmaceutical form:

yellowish white powder

Patient Information leaflet

Drug Information Sheet("Kusuri-no-Shiori")
Internal
Published: 12/2008
The information on this sheet is based on approvals granted by the
Japanese regulatory authority. Approval
details may vary by country. Medicines have adverse reactions (risks)
as well as efficacies (benefits). It is
important to minimize adverse reactions and maximize efficacy. To
obtain a better therapeutic response,
patients should understand their medication and cooperate with the
treatment.
BRAND NAME:
LEUKERIN POWDER 10%
ACTIVE INGREDIENT:
Mercaptopurine
DOSAGE FORM:
yellowish white powder
IMPRINT OR PRINT ON WRAPPING:
EFFECTS OF THIS MEDICINE
This medicine suppresses excessive growth of abnormal cells by
inhibiting synthesis of
adenine and guanine nucleotide which are components of DNA required
for the growth of
cells.
It is usually used for the remission of subjective and objective
symptoms in acute leukemia
and chronic myeloid leukemia.
THE FOLLOWING PATIENTS MAY NEED TO BE CAREFUL WHEN USING THIS
MEDICINE.BE SURE TO TELL YOUR DOCTOR
AND PHARMACIST.
・If you ever experienced any allergic reaction (itch, rash, etc.) to
any medicines or foods.
If you are a patient with hepatic or renal disorder, myelosuppression,
complicating infection,
or varicella (chickenpox).
・If you are pregnant or breastfeeding.
・If you are taking any other medicinal products. (Some medicines may
interact to enhance or
diminish medicinal effects. Beware of over-the-counter medicines and
dietary supplements
as well as other prescription medicines.)
DOSING SCHEDULE (HOW TO TAKE THIS MEDICINE)
・
Your dosing schedule prescribed by your doctor is((         

to be written by a healthcare
professional
))
・General dosage regimen: For adults, take 0.02 to 0.03 g/kg (2 to 3
mg of the active
ingredient) daily, individually or concurrently with other medicine.
After the remission, take
smaller amounts of remission-inducing dose, individually or
concurrently with other
medicine. The dosage may be adjusted according to the age or sympt