KEFUROX POWDER FOR SOLUTION

Country: Canada

Language: English

Source: Health Canada

Active ingredient:

CEFUROXIME (CEFUROXIME SODIUM)

Available from:

PHARMACEUTICAL PARTNERS OF CANADA INC

ATC code:

J01DC02

INN (International Name):

CEFUROXIME

Dosage:

750MG

Pharmaceutical form:

POWDER FOR SOLUTION

Composition:

CEFUROXIME (CEFUROXIME SODIUM) 750MG

Administration route:

INTRAVENOUS

Units in package:

750MG

Prescription type:

Prescription

Therapeutic area:

SECOND GENERATION CEPHALOSPORINS

Product summary:

Active ingredient group (AIG) number: 0122448004; AHFS:

Authorization status:

CANCELLED POST MARKET

Authorization date:

2008-02-13

Summary of Product characteristics

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Kefurox – Product Monograph
PRODUCT MONOGRAPH
PR
KEFUROX
®
(CEFUROXIME FOR INJECTION, USP)
IV
ANTIBIOTIC
Pharmaceutical Partners of Canada Inc.
Date of Preparation:
45 Vogell Road, Suite 200
January 14, 2008
Richmond Hill, ON L4B 3P6
Control No.: 119197
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Kefurox – Product Monograph
NAME OF DRUG
KEFUROX
(cefuroximefor injection, USP)
THERAPEUTIC CLASSIFICATION
IV
Antibiotic
ACTION
_In vitro_ tests demonstrate that the bactericidal action of
cefuroxime results from the
inhibition of the transpeptidase and carboxypeptidase enzymes, thus
inhibiting cell
wall synthesis.
INDICATIONS
KEFUROX (cefuroxime) may be indicated for the treatment of patients
with infections
caused by susceptible strains of the designated microorganisms in the
following
diseases:
LOWER RESPIRATORY TRACT INFECTIONS: Pneumonia caused by_ Streptococcus
_
_pneumoniae_. _Haemophilus influenzae_ including ampicillin-resistant
strains, _Klebsiella_
species, _Staphylococcus aureus_ (penicillinase- and non-penicillinase
producing)
including ampicillin-resistant (but not methicillin-resistant)
strains. _Streptococcus _
_pyogenes_ and _Escherichia coli_.
URINARY TRACT INFECTIONS: Caused by _Escherichia coli_ and
_Klebsiella_ species.
SOFT TISSUE INFECTIONS: Caused by _Staphylococcus aureus_
(penicillinase- and non-
penicillinase producing) including ampicillin-resistant (but not
methicillin-resistant)
strains. _Streptococcus pyogenes_, _Escherichia coli _and_ Klebsiella_
species.
GONORRHEA: Caused by _Neisseria gonorrhea_ (penicillinase- and
non-penicillinase
producing strains) including ampicillin-resistant strains.
MENINGITIS: Caused by _Staphylococcus aureus_ (penicillinase- and
non-penicillinase
producing) including ampicillin-resistant (but not
methicillin-resistant) strains,
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Kefurox – Product Monograph
2
_Streptococcus pneumoniae_, _Haemo