HYALOVET- hyaluronate sodium liquid

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

HYALURONATE SODIUM (UNII: YSE9PPT4TH) (HYALURONIC ACID - UNII:S270N0TRQY)

Available from:

Boehringer Ingelheim Animal Health USA Inc.

Administration route:

INTRA-ARTICULAR

Prescription type:

PRESCRIPTION

Therapeutic indications:

Hyalovet is indicated for the intra-articular treatment of carpal or fetlock joint dysfunction in horses due to acute or chronic, non-infectious synovitis associated with equine osteoarthritis. There are no known contraindications.

Product summary:

Hyalovet Veterinary Injection is supplied in a 2 mL syringe or vial containing 20 mg hyaluronate sodium per 2 mL. NDC 0010-4705-01: 2 mL syringe NDC 0010-4705-02: 2 mL vial

Authorization status:

New Animal Drug Application

Summary of Product characteristics

HYALOVET- HYALURONATE SODIUM LIQUID
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
----------
HYALOVET
(HYALURONATE SODIUM)
VETERINARY INJECTION
For intra-articular administration in horses only
CAUTION:
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION:
Hyaluronic acid is the prototype of a wide range of saccharide
biopolymers
(glycosaminoglycans or mucopolysaccharides) consisting of repeating
disaccharide
units of N-acetyl-D-glucosamine and D-glucuronic acid linked by beta
1-3 and beta 1-4
glycosidic bonds. A component of all mammalian connective tissue,
hyaluronic acid
confers viscoelastic and lubricating properties to synovial fluid and
structural integrity
to cartilage matrix . As a therapeutic agent, hyaluronic acid injected
into arthritic joints
has been shown, in a variety of animal model systems including horses
, to improve joint
function and to activate tissue repair processes in articular
cartilage.
Hyalovet (hyaluronate sodium) is clear, colorless, viscous solution of
a specific fraction
of highly purified hyaluronic acid obtained by a molecular filtration
procedure from
biological material (rooster combs). The specific hyaluronic acid
fraction from which
Hyalovet is made has a high degree of molecular definition with an
average molecular
weight of 500,000-730,000 D.
Each filled 2 mL glass syringe or 2 mL glass vial contains:
Hyaluronate sodium........................................20.0 mg
Sodium chloride..............................................17.0 mg
Monobasic sodium phosphate...........................0.1 mg
Dibasic sodium phosphate.................................1.2 mg
Water for injection.......................................q.s., 2 mL
INDICATIONS:
Hyalovet is indicated for the intra-articular treatment of carpal or
fetlock joint
dysfunction in horses due to acute or chronic, non-infectious
synovitis associated with
equine osteoarthritis.
DOSAGE AND ADMINISTRATION:
The recommended dose of Hyalovet (hyaluronate sodium) is 2 mL (20 mg
hyaluronate