País: Estats Units
Idioma: anglès
Font: NLM (National Library of Medicine)
HYALURONATE SODIUM (UNII: YSE9PPT4TH) (HYALURONIC ACID - UNII:S270N0TRQY)
Boehringer Ingelheim Animal Health USA Inc.
INTRA-ARTICULAR
PRESCRIPTION
Hyalovet is indicated for the intra-articular treatment of carpal or fetlock joint dysfunction in horses due to acute or chronic, non-infectious synovitis associated with equine osteoarthritis. There are no known contraindications.
Hyalovet Veterinary Injection is supplied in a 2 mL syringe or vial containing 20 mg hyaluronate sodium per 2 mL. NDC 0010-4705-01: 2 mL syringe NDC 0010-4705-02: 2 mL vial
New Animal Drug Application
HYALOVET- HYALURONATE SODIUM LIQUID BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC. ---------- HYALOVET (HYALURONATE SODIUM) VETERINARY INJECTION For intra-articular administration in horses only CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION: Hyaluronic acid is the prototype of a wide range of saccharide biopolymers (glycosaminoglycans or mucopolysaccharides) consisting of repeating disaccharide units of N-acetyl-D-glucosamine and D-glucuronic acid linked by beta 1-3 and beta 1-4 glycosidic bonds. A component of all mammalian connective tissue, hyaluronic acid confers viscoelastic and lubricating properties to synovial fluid and structural integrity to cartilage matrix . As a therapeutic agent, hyaluronic acid injected into arthritic joints has been shown, in a variety of animal model systems including horses , to improve joint function and to activate tissue repair processes in articular cartilage. Hyalovet (hyaluronate sodium) is clear, colorless, viscous solution of a specific fraction of highly purified hyaluronic acid obtained by a molecular filtration procedure from biological material (rooster combs). The specific hyaluronic acid fraction from which Hyalovet is made has a high degree of molecular definition with an average molecular weight of 500,000-730,000 D. Each filled 2 mL glass syringe or 2 mL glass vial contains: Hyaluronate sodium........................................20.0 mg Sodium chloride..............................................17.0 mg Monobasic sodium phosphate...........................0.1 mg Dibasic sodium phosphate.................................1.2 mg Water for injection.......................................q.s., 2 mL INDICATIONS: Hyalovet is indicated for the intra-articular treatment of carpal or fetlock joint dysfunction in horses due to acute or chronic, non-infectious synovitis associated with equine osteoarthritis. DOSAGE AND ADMINISTRATION: The recommended dose of Hyalovet (hyaluronate sodium) is 2 mL (20 mg hyaluronate Llegiu el document complet