INTRALIPID 20% EMULSION

Χώρα: Καναδάς

Γλώσσα: Αγγλικά

Πηγή: Health Canada

Δραστική ουσία:

SOYBEAN OIL

Διαθέσιμο από:

FRESENIUS KABI CANADA LTD

Φαρμακολογική κατηγορία (ATC):

B05BA02

INN (Διεθνής Όνομα):

FAT EMULSIONS

Δοσολογία:

20%

Φαρμακοτεχνική μορφή:

EMULSION

Σύνθεση:

SOYBEAN OIL 20%

Οδός χορήγησης:

INTRAVENOUS

Μονάδες σε πακέτο:

100/250/500/1000 ML

Τρόπος διάθεσης:

Ethical

Θεραπευτική περιοχή:

CALORIC AGENTS

Περίληψη προϊόντος:

Active ingredient group (AIG) number: 0124460003; AHFS:

Καθεστώς αδειοδότησης:

APPROVED

Ημερομηνία της άδειας:

1997-11-04

Αρχείο Π.Χ.Π.

1
PRODUCT MONOGRAPH
PR
INTRALIPID
®
Lipid Injectable Emulsion, Mfr. Std.
Soybean Oil 10%, 20%, 30% w/v
Lipid Emulsions for Intravenous Nutrition
FRESENIUS KABI CANADA LTD.
165 Galaxy Blvd, Suite 100
Toronto, ON M9W 0C8
Date of Revision:
January 6, 2020
Submission Control No.: 233169
2
_PRODUCT MONOGRAPH _
_ _
PR
INTRALIPID
®
Lipid Injectable Emulsion, Mfr. Std.
Soybean Oil 10%, 20%, 30% w/v
_THERAPEUTIC CLASSIFICATION _
Lipid Emulsions for Intravenous Nutrition
_ACTION _
Intralipid acts as an energy source in patients for whom the usual
intravenous therapy would not
be adequate and as a source of essential fatty acids to prevent
essential fatty acid deficiency.
Providing sufficient amounts of calories to satisfy basal metabolic
requirements plus the
additional needs imposed by disease and/or surgical stress can be
difficult and sometimes even
impossible. If the intravenous route has to be used and only
carbohydrates are given as an
energy source large amounts of fluid or very hypertonic solutions must
be employed. Fat has an
energy value a little more than twice that of carbohydrates, and is
therefore an excellent source
of energy for use in parenteral nutrition. By including fat emulsion
in the nutritional programme
a balanced intravenous nutrition can be achieved.
Moreover, INTRALIPID is practically isotonic with blood which makes it
possible to infuse
large amounts of energy providing substrate in a small volume of fluid
via peripheral veins. This
property makes possible peripheral vein infusion of solutions that
otherwise have to be
administered by central veins, (see ADMINISTRATION).
Fat emulsions may be used to supply up to 40% of the non-protein
energy requirements of the
patient. Each mL of Intralipid 10% contains 4.6 kJ (1.1 kcal), each mL
of Intralipid 20%
3
contains 8.4 kJ (2.0 kcal) and each mL of Intralipid 30% contains 12.6
kJ (3.0 kcal). Half a litre
of Intralipid 10%, Intralipid 20% and Intralipid 30% thus contains 2.3
MJ (550 kcal), 4.2 MJ
(1000 kcal) and 6.3 MJ (1 500 kcal), respectively. Part