País: Canadà
Idioma: anglès
Font: Health Canada
SOYBEAN OIL
FRESENIUS KABI CANADA LTD
B05BA02
FAT EMULSIONS
20%
EMULSION
SOYBEAN OIL 20%
INTRAVENOUS
100/250/500/1000 ML
Ethical
CALORIC AGENTS
Active ingredient group (AIG) number: 0124460003; AHFS:
APPROVED
1997-11-04
1 PRODUCT MONOGRAPH PR INTRALIPID ® Lipid Injectable Emulsion, Mfr. Std. Soybean Oil 10%, 20%, 30% w/v Lipid Emulsions for Intravenous Nutrition FRESENIUS KABI CANADA LTD. 165 Galaxy Blvd, Suite 100 Toronto, ON M9W 0C8 Date of Revision: January 6, 2020 Submission Control No.: 233169 2 _PRODUCT MONOGRAPH _ _ _ PR INTRALIPID ® Lipid Injectable Emulsion, Mfr. Std. Soybean Oil 10%, 20%, 30% w/v _THERAPEUTIC CLASSIFICATION _ Lipid Emulsions for Intravenous Nutrition _ACTION _ Intralipid acts as an energy source in patients for whom the usual intravenous therapy would not be adequate and as a source of essential fatty acids to prevent essential fatty acid deficiency. Providing sufficient amounts of calories to satisfy basal metabolic requirements plus the additional needs imposed by disease and/or surgical stress can be difficult and sometimes even impossible. If the intravenous route has to be used and only carbohydrates are given as an energy source large amounts of fluid or very hypertonic solutions must be employed. Fat has an energy value a little more than twice that of carbohydrates, and is therefore an excellent source of energy for use in parenteral nutrition. By including fat emulsion in the nutritional programme a balanced intravenous nutrition can be achieved. Moreover, INTRALIPID is practically isotonic with blood which makes it possible to infuse large amounts of energy providing substrate in a small volume of fluid via peripheral veins. This property makes possible peripheral vein infusion of solutions that otherwise have to be administered by central veins, (see ADMINISTRATION). Fat emulsions may be used to supply up to 40% of the non-protein energy requirements of the patient. Each mL of Intralipid 10% contains 4.6 kJ (1.1 kcal), each mL of Intralipid 20% 3 contains 8.4 kJ (2.0 kcal) and each mL of Intralipid 30% contains 12.6 kJ (3.0 kcal). Half a litre of Intralipid 10%, Intralipid 20% and Intralipid 30% thus contains 2.3 MJ (550 kcal), 4.2 MJ (1000 kcal) and 6.3 MJ (1 500 kcal), respectively. Part Llegiu el document complet