Χώρα: Αυστραλία
Γλώσσα: Αγγλικά
Πηγή: Department of Health (Therapeutic Goods Administration)
Ceftazidime
Aspen Pharmacare Australia Pty Ltd
Medicine Registered
FORTUM 1 FORTUM INJECTION _Ceftazidime _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET? Please read this leaflet carefully before you use Fortum. This leaflet answers some common questions about Fortum. It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Sometimes new risks are found even when a medicine has been used for many years. Your doctor has weighed the expected benefits of you taking Fortum against the risks this medicine could have for you. If you have any concerns about taking this medicine, ask your doctor or pharmacist. Keep this leaflet with the medicine. You may need to read it again. WHAT IS FORTUM USED FOR? Fortum belongs to a group of medicines called cephalosporins. Fortum is used to treat a wide range of infections caused by bacteria. These infections may affect the chest (bronchitis or pneumonia), ears, nose, throat, bladder and urinary tract, skin and soft tissue, stomach or bones. Fortum works by killing the bacteria that cause these infections. Your doctor may have prescribed Fortum for another reason. There is no evidence that Fortum injection is addictive. BEFORE YOU ARE GIVEN FORTUM _WHEN YOU MUST NOT BE GIVEN _ _IT: _ You must not be given Fortum if: * you have ever had an allergic reaction to cephalosporins, penicillins or any of the ingredients listed toward the end of this leaflet. (See "Ingredients") * the expiry date (EXP) printed on the pack has passed. * the packaging is torn or shows signs of tampering _TELL YOUR DOCTOR IF: _ You must tell your doctor if: * you are allergic Διαβάστε το πλήρες έγγραφο
1 PRODUCT INFORMATION FORTUM NAME OF THE MEDICINE: Fortum (ceftazidime as pentahydrate). Chemical structure: O H 2 .5 O H O CH 3 N S S N O O N + O NH H H O N O N H 2 CH 3 CAS Registry number: 72558-82-8 DESCRIPTION: Fortum is a cephalosporin antibiotic for use by injection only. It is supplied as a white to faintly yellow powder in vials containing 1 g and 2 g ceftazidime (as pentahydrate) with sodium carbonate anhydrous (116 mg per gram of ceftazidime). On the addition of Water for Injections, Fortum Injection dissolves with effervescence to produce a solution for injection. Fortum Injection contains approximately 52 mg (2.3 mEq) of sodium per gram of ceftazidime. 1.164 g of pure ceftazidime pentahydrate is equivalent to 1 g ceftazidime free acid. For laboratory tests associated with ceftazidime administration, ceftazidime pentahydrate should be used. PHARMACOLOGY: PHARMACOKINETICS: Absorption of ceftazidime after oral administration is negligible, therefore Fortum is intended for parenteral use only. In man after a single intramuscular administration of 500 mg and 1 g, mean peak serum levels of 18 and 37 mg/L respectively are achieved at 1 hour falling to 8 and 2 mg/L and 20 and 5 mg/L at 4 and 8 hours respectively for the two doses. Five minutes after an intravenous bolus injection of 500 mg, 1 g and 2 g, mean serum levels are respectively 46, 87 and 170 mg/L falling to 17 and 6 mg/L, 32 and 10 mg/L and 85 and 15 mg/L at 1 and 4 hours respectively with the three doses. The serum half-life in adults Διαβάστε το πλήρες έγγραφο