ATENOLOL RBX Atenolol 50 mg film coated tablets blister pack

Χώρα: Αυστραλία

Γλώσσα: Αγγλικά

Πηγή: Department of Health (Therapeutic Goods Administration)

Δραστική ουσία:

Atenolol

Διαθέσιμο από:

Sun Pharma ANZ Pty Ltd

INN (Διεθνής Όνομα):

Atenolol

Φύλλο οδηγιών χρήσης

PIP-ATENOLOL
CONSUMER MEDICINE INFORMATION
September 2013 / Version 1
COMMERCIAL-IN-CONFIDENCE
Ipca Pharma (Australia) Pty. Ltd-atenolol 25mg, 50mg & 100 mg film
coated tablets 2013
- 1 -
PIP-ATENOLOL
(ATENOLOL 25MG, 50MG & 100MG FILM COATED TABLETS)
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common questions about PIP-ATENOLOL.
It does not contain all the available information. It does not take
the place of talking to your doctor
or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the
risks of you taking PIP-
ATENOLOL against the benefits they expect it will have for you.
This medicine may also be used in emergency situations where you may
be unconscious. In this
case, this leaflet may be given to you after the medicine has been
used.
IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR
OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT PIP-ATENOLOL IS USED FOR
PIP-ATENOLOL belongs to a group of medicines called beta-blockers.
It works by affecting the body's response to certain nerve impulses,
especially in the heart. As a
result, it decreases the heart's need for blood and oxygen and
therefore reduces the amount of work
the heart has to do. It widens the blood vessels in the body, causing
blood pressure to fall. It also
helps the heart to beat more regularly.
PIP-ATENOLOL is used to:

lower high blood pressure, which is called hypertension

prevent angina

treat irregular heart rhythm or beat called arrhythmias

treat heart attacks, or reduce your risk of heart complications
following a heart attack
PIP-ATENOLOL may be either used alone or in combination with other
medicines to treat your
condition.
PIP-ATENOLOL may also be used in emergency situations or during
surgery to treat a fast heart
beat before, during or after surgery.
PIP-ATENOLOL
CONSUMER MEDICINE INFORMATION
September 2013 / Version 1
COMMERCIAL-IN-CONFIDENCE
Ipca Pharma (Australia) Pty. Ltd-atenolol 25mg, 50mg & 100 mg f

Αρχείο Π.Χ.Π.

PRODUCT INFORMATION
ATENOLOL RBX
ATENOLOL 25 MG, 50 MG, 100 MG FILM-COATED TABLETS
NAME OF THE MEDICINE
Atenolol
Chemical name:
_(RS)-_
4-(2-hydroxy-3-isopropylaminopropoxy)phenyl]acetamide.
Structure:
CAS [
_29122-68-7_
]
C
14
H
22
N
2
O
3
MW: 266.3
Atenolol is a white or almost white powder, sparingly soluble in
water, soluble in ethanol,
slightly soluble in methylene chloride and practically insoluble in
ether.
DESCRIPTION
Atenolol:
Beta-adrenoreceptor blocking agent structurally related to propranolol
and differing from it by
substitution on the aromatic ring.
Atenolol tablets: Each tablet contains 25 mg, 50 mg or 100 mg,
respectively, of the active
substance atenolol.
The tablets also contain magnesium stearate, maize starch, sodium
lauryl sulfate, colloidal
anhydrous silica, sodium starch glycollate type A, heavy magnesium
carbonate, hypromellose,
macrogol 6000, titanium dioxide, purified talc.
PHARMACOLOGY
Atenolol is a beta-adrenoreceptor blocking drug which acts
preferentially on beta- receptors in
the heart. Selectivity decreases with increasing dose. It has little
intrinsic sympathomimetic
activity and no membrane stabilising activity. Atenolol is a racemic
mixture and its activity
resides in the S(-) enantiomer. It reduces raised blood pressure by an
unknown mechanism and
also inhibits exercise induced tachycardia and decreases plasma renin
concentration. It causes
slight airways obstruction but less than that seen with nonselective
beta-blockers. The inhibition
ATENOLOL RBX PI V3
1
of exercise induced tachycardia is correlated with blood levels but
there is no correlation
between plasma concentrations and antihypertensive effect. ATENOLOL
RBX is effective and
well tolerated in most ethnic populations although the response may be
less in Afro-Caribbean
black patients.
The possible mechanism of the anti-anginal activity of Atenolol
appears to be due to a reduction
in left ventricular work and oxygen utilisation resulting (mainly)
from the decrease in heart rate
and contractility.
The anti-arrhythmic ef