Страна: Австралия
Език: английски
Източник: Department of Health (Therapeutic Goods Administration)
Atenolol
Sun Pharma ANZ Pty Ltd
Atenolol
PIP-ATENOLOL CONSUMER MEDICINE INFORMATION September 2013 / Version 1 COMMERCIAL-IN-CONFIDENCE Ipca Pharma (Australia) Pty. Ltd-atenolol 25mg, 50mg & 100 mg film coated tablets 2013 - 1 - PIP-ATENOLOL (ATENOLOL 25MG, 50MG & 100MG FILM COATED TABLETS) CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about PIP-ATENOLOL. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking PIP- ATENOLOL against the benefits they expect it will have for you. This medicine may also be used in emergency situations where you may be unconscious. In this case, this leaflet may be given to you after the medicine has been used. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT PIP-ATENOLOL IS USED FOR PIP-ATENOLOL belongs to a group of medicines called beta-blockers. It works by affecting the body's response to certain nerve impulses, especially in the heart. As a result, it decreases the heart's need for blood and oxygen and therefore reduces the amount of work the heart has to do. It widens the blood vessels in the body, causing blood pressure to fall. It also helps the heart to beat more regularly. PIP-ATENOLOL is used to: lower high blood pressure, which is called hypertension prevent angina treat irregular heart rhythm or beat called arrhythmias treat heart attacks, or reduce your risk of heart complications following a heart attack PIP-ATENOLOL may be either used alone or in combination with other medicines to treat your condition. PIP-ATENOLOL may also be used in emergency situations or during surgery to treat a fast heart beat before, during or after surgery. PIP-ATENOLOL CONSUMER MEDICINE INFORMATION September 2013 / Version 1 COMMERCIAL-IN-CONFIDENCE Ipca Pharma (Australia) Pty. Ltd-atenolol 25mg, 50mg & 100 mg f Прочетете целия документ
PRODUCT INFORMATION ATENOLOL RBX ATENOLOL 25 MG, 50 MG, 100 MG FILM-COATED TABLETS NAME OF THE MEDICINE Atenolol Chemical name: _(RS)-_ 4-(2-hydroxy-3-isopropylaminopropoxy)phenyl]acetamide. Structure: CAS [ _29122-68-7_ ] C 14 H 22 N 2 O 3 MW: 266.3 Atenolol is a white or almost white powder, sparingly soluble in water, soluble in ethanol, slightly soluble in methylene chloride and practically insoluble in ether. DESCRIPTION Atenolol: Beta-adrenoreceptor blocking agent structurally related to propranolol and differing from it by substitution on the aromatic ring. Atenolol tablets: Each tablet contains 25 mg, 50 mg or 100 mg, respectively, of the active substance atenolol. The tablets also contain magnesium stearate, maize starch, sodium lauryl sulfate, colloidal anhydrous silica, sodium starch glycollate type A, heavy magnesium carbonate, hypromellose, macrogol 6000, titanium dioxide, purified talc. PHARMACOLOGY Atenolol is a beta-adrenoreceptor blocking drug which acts preferentially on beta- receptors in the heart. Selectivity decreases with increasing dose. It has little intrinsic sympathomimetic activity and no membrane stabilising activity. Atenolol is a racemic mixture and its activity resides in the S(-) enantiomer. It reduces raised blood pressure by an unknown mechanism and also inhibits exercise induced tachycardia and decreases plasma renin concentration. It causes slight airways obstruction but less than that seen with nonselective beta-blockers. The inhibition ATENOLOL RBX PI V3 1 of exercise induced tachycardia is correlated with blood levels but there is no correlation between plasma concentrations and antihypertensive effect. ATENOLOL RBX is effective and well tolerated in most ethnic populations although the response may be less in Afro-Caribbean black patients. The possible mechanism of the anti-anginal activity of Atenolol appears to be due to a reduction in left ventricular work and oxygen utilisation resulting (mainly) from the decrease in heart rate and contractility. The anti-arrhythmic ef Прочетете целия документ