Χώρα: Αυστραλία
Γλώσσα: Αγγλικά
Πηγή: Department of Health (Therapeutic Goods Administration)
Albumin
CSL Limited
Medicine Registered
Albumex 20 AU CMI 10.00 Page 1 of 2 ALBUMEX ® 20_ _ Human albumin, solution for intravenous infusion Consumer Medicine Information 10 ML AUST R 31820 100 ML AUST R 46283 WHAT IS IN THIS LEAFLET? This leaflet answers some common questions about Albumex ® 20. It does not contain all the available information about Albumex ® 20. It does NOT take the place of talking to your doctor. All medicines have benefits and risks. Your doctor has weighed the benefits that Albumex ® 20 will have for you against the risks. IF YOU HAVE ANY CONCERNS ABOUT USING THIS MEDICINE, ASK YOUR DOCTOR. FOLLOW YOUR DOCTOR'S ADVICE EVEN IF IT IS DIFFERENT FROM WHAT THIS LEAFLET SAYS. PLEASE READ THIS LEAFLET CAREFULLY AND KEEP IT FOR FUTURE REFERENCE. The information in this leaflet is subject to change. Please check with your doctor whether there is any new information about this medicine that you should know since you were last treated with this medicine. WHAT ALBUMEX ® 20 IS USED FOR Albumex ® 20 may be used: • in an acutely ill patient when the amount of protein in their blood is low (hypoproteinaemia) • to replace fluid in the blood vessels due to acute loss of blood or plasma (plasma is the non-cellular part of the blood) • to treat extensive burns • to treat a serious lung condition (respiratory distress syndrome) • in procedures where the patient’s blood is purified (haemodialysis) • in procedures where the patient’s plasma is replaced (plasma exchange). The main functions of Albumex ® 20 are to replace and retain fluid in the blood vessels and to carry other chemicals through the blood stream. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY ALBUMEX ® 20 HAS BEEN PRESCRIBED FOR YOU. BEFORE Διαβάστε το πλήρες έγγραφο
Albumex 20 AU PI 10.00 Page 1 of 9 Product Information ALBUMEX ® 20 HUMAN ALBUMIN 20% (200 G/L) AUSTRALIA NAME OF THE MEDICINE Human albumin, solution for intravenous infusion. DESCRIPTION Albumex ® 20 is manufactured from human plasma collected by the Australian Red Cross Blood Service. Albumex ® 20 is a clear, slightly viscous liquid; it is almost colourless, yellow, amber or green. It is prepared using predominantly chromatographic techniques. It is a sterile, preservative-free 20% w/v human albumin solution. It is hyperoncotic and hypo-osmotic compared to human serum. It has a nominal osmolality of 130 mOsm/kg, is hypotonic and the pH is 6.7 to 7.3. The manufacturing process for Albumex ® 20 contains dedicated steps to reduce the possibility of virus transmission including pasteurisation (heating at 60°C for 10 hours) and incubation at low pH to inactivate viruses. The composition of Albumex ® 20 is as follows: Human Albumin 200 g/L Sodium 48 – 100 mmol/L Octanoate 32 mmol/L PHARMACOLOGY Albumin accounts quantitatively for more than half of the total protein in the plasma and represents about 10% of the protein synthesis activity of the liver. The metabolic half-life of albumin _in vivo_ is about 19 days and the turnover in an adult is approximately 15 g per day. There is rapid interchange of albumin between the intra and extravascular spaces. Albumex ® 20 has two main functions: maintenance of plasma colloid osmotic pressure and carriage of intermediate products in the transport and exchange of tissue metabolites. The beneficial effect of human albumin for fluid resuscitation is thought to result principally from its contribution to colloid osmotic pressure (i.e. oncotic pressure). Albumex ® 20 is hyperoncotic with hum Διαβάστε το πλήρες έγγραφο