PHARMANIAGA VITAMIN B COMPLEX TABLET

Land: Malaysia

Sprache: Englisch

Quelle: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

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Herunterladen Fachinformation (SPC)
22-02-2021

Wirkstoff:

RIBOFLAVINE; THIAMINE MONONITRATE; Nicotinamide

Verfügbar ab:

PHARMANIAGA MANUFACTURING BERHAD

INN (Internationale Bezeichnung):

RIBOFLAVINE; THIAMINE MONONITRATE; Nicotinamide

Einheiten im Paket:

6930 Tablets

Hergestellt von:

PHARMANIAGA MANUFACTURING BERHAD

Fachinformation

                                artwork prepared by: cynthia yap
email: graphic@focusprint.info (graphic Dept)
customer
PHARMANIAGA MANUFACTURING BERHAD
description
VITAMIN B COMPLEX LEAFLET
size
attn
148.5 X 210MM
date
22.02.21
FOCUSPRINT
SDN BHD
DATE:
t: 603-8766 6030 f: 603-8766 6033 (Factory)
website: www.focusprint.info
1
PLEASE CHOP & SIGN FOR APPROVAL
colours
BLACK
process colours:
spot colours:
148.5mm
210mm
IMPORTANT !
PLEASE NOTE THAT THIS COLOUR PRINT IS FOR VISUAL PURPOSE ONLY. OUTPUT
COLOUR MIGHT DIFFER IN ACTUAL PRODUCTION.
DESCRIPTION
Yellow, round, flat beveled edge tablet with ‘KK’ marking on
one side and plain on the other.
COMPOSITION
Each tablet contains:
Thiamine Mononitrate 1.0 mg equivalent to Thiamine 0.92mg.
Riboflavine 1.5 mg
Nicotinamide 10.0 mg
ACTIONS
PHARMACOLOGICAL PROPERTIES
Thiamine mononitrate is a vitamin (B1)
Riboflavine is a vitamin (B2)
Nicotinamide is a vitamin (B3)
PHARMACODYNAMIC PROPERTIES
Vitamin B complex is a group of water-soluble factors that are more or
less
closely associated with their natural occurrence. Almost every
B-complex vitamin
is
part
of
co-enzyme
necessary
for
protein,
carbohydrate,
or
fatty
acid
metabolism.
PHARMACOKINETIC PROPERTIES
Thiamine is absorbed from the gastrointestinal tract and is widely
distributed to
most body tissues. It is not stored to any appreciable extent in the
body and
amounts in excess of requirements are excreted in the urine as
unchanged
thiamine or metabolites.
Riboflavine
is
rapidly
absorbed
from
the
gastrointestinal
tract. Although
riboflavine is widely distributed to body tissue, little is stored in
the body.
Riboflavin is converted in the body to the coenzyme flavine
mononucleotide
(FMN) and then to another coenzyme flavine adenine dinucleotide (FAD).
About
60% FMN and FAD are bound to plasma proteins. Riboflavine is excreted
in the
urine, partly as metabolites. As the dose increases, more significant
amounts
are excreted unchanged.
Nicotinamide is readily absorbed from the gastrointestinal tract
following oral
administration and is widely distributed
                                
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