Land: Malaysia
Sprache: Englisch
Quelle: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
RIBOFLAVINE; THIAMINE MONONITRATE; Nicotinamide
PHARMANIAGA MANUFACTURING BERHAD
RIBOFLAVINE; THIAMINE MONONITRATE; Nicotinamide
6930 Tablets
PHARMANIAGA MANUFACTURING BERHAD
artwork prepared by: cynthia yap email: graphic@focusprint.info (graphic Dept) customer PHARMANIAGA MANUFACTURING BERHAD description VITAMIN B COMPLEX LEAFLET size attn 148.5 X 210MM date 22.02.21 FOCUSPRINT SDN BHD DATE: t: 603-8766 6030 f: 603-8766 6033 (Factory) website: www.focusprint.info 1 PLEASE CHOP & SIGN FOR APPROVAL colours BLACK process colours: spot colours: 148.5mm 210mm IMPORTANT ! PLEASE NOTE THAT THIS COLOUR PRINT IS FOR VISUAL PURPOSE ONLY. OUTPUT COLOUR MIGHT DIFFER IN ACTUAL PRODUCTION. DESCRIPTION Yellow, round, flat beveled edge tablet with ‘KK’ marking on one side and plain on the other. COMPOSITION Each tablet contains: Thiamine Mononitrate 1.0 mg equivalent to Thiamine 0.92mg. Riboflavine 1.5 mg Nicotinamide 10.0 mg ACTIONS PHARMACOLOGICAL PROPERTIES Thiamine mononitrate is a vitamin (B1) Riboflavine is a vitamin (B2) Nicotinamide is a vitamin (B3) PHARMACODYNAMIC PROPERTIES Vitamin B complex is a group of water-soluble factors that are more or less closely associated with their natural occurrence. Almost every B-complex vitamin is part of co-enzyme necessary for protein, carbohydrate, or fatty acid metabolism. PHARMACOKINETIC PROPERTIES Thiamine is absorbed from the gastrointestinal tract and is widely distributed to most body tissues. It is not stored to any appreciable extent in the body and amounts in excess of requirements are excreted in the urine as unchanged thiamine or metabolites. Riboflavine is rapidly absorbed from the gastrointestinal tract. Although riboflavine is widely distributed to body tissue, little is stored in the body. Riboflavin is converted in the body to the coenzyme flavine mononucleotide (FMN) and then to another coenzyme flavine adenine dinucleotide (FAD). About 60% FMN and FAD are bound to plasma proteins. Riboflavine is excreted in the urine, partly as metabolites. As the dose increases, more significant amounts are excreted unchanged. Nicotinamide is readily absorbed from the gastrointestinal tract following oral administration and is widely distributed Lesen Sie das vollständige Dokument