Land: Australien
Sprache: Englisch
Quelle: APVMA (Australian Pesticides and Veterinary Medicines Authority)
CLOPROSTENOL AS SODIUM
PARNELL TECHNOLOGIES PTY LTD
cloprostenol as Na salt(250ug/mL)
PARENTERAL LIQUID/SOLUTION/SUSPENSION
CLOPROSTENOL AS SODIUM PROSTAGLANDIN Active 250.0 ug/ml
100mL
VM - Veterinary Medicine
PARNELL TECHNOLOGIES
COW | BOVINE | FEMALE CATTLE
ENDOCRINE SYSTEM
CYSTIC OVARIES | INDUCE ABORTION | INDUCTION OF PARTURITION | PYOMETRA | SUB OESTRUS | SYNCHRONISATION OF OESTRUS | INDUCTION OF CALVING | SILENT HEAT
Poison schedule: 4; Withholding period: WHP:MEAT:DO NOT use less than 1 day be fore slaughter for human consumption. M ILK:NIL; Host/pest details: COW: [CYSTIC OVARIES, INDUCE ABORTION, INDUCTION OF PARTURITION, PYOMETRA, SUB OESTRUS, SYNCHRONISATION OF OESTRUS]; Poison schedule: 4; Withholding period: ; Host/pest details: COW: [CYSTIC OVARIES, INDUCE ABORTION, INDUCTION OF PARTURITION, PYOMETRA, SUB OESTRUS, SYNCHRONISATION OF OESTRUS]; For luteolysis of functional corpora lutea in cows.Do not use in pregnant animals when abortion or induced parturition is not the objective. Do not administer intravenously.
Registered
2023-07-01
APPROVED LABEL APPROVED LABEL Info PEST Verified APPROVED LABEL Company: PARNELL Laboratories (Aust) Pty Ltd File Name: 49746_47366_Leaflet_MPL_V01.pdf Dimensions: 450mm x 95mm Scale: 90% (if printed on A3 sheet) Date: 20/05/2009 Colours: BLACK 50247b-01 PRESCRIPTION ANIMAL REMEDY KEEP OUT OF REACH OF CHILDREN FOR ANIMAL TREATMENT ONLY ACTIVE CONSTITUENT CLOPROSTENOL (as the sodium salt) 250 μ g/mL FOR LUTEOLYSIS OF FUNCTIONAL CORPORA LUTEA IN COWS. PHARMACOLOGY Prostaglandins (PGs) are 20-carbon unsaturated fatty acids which consist of a cyclopentane ring with two aliphatic side chains. They are synthesised from free arachidonic acid in most major tissues in the body and serve as local hormones, acting on tissues near their site of synthesis. PGs are structurally classified into nine major groups, A to I, each containing subgroups denoted by the subscripts 1, 2 and 3. In domestic animals the most important PG appears to be PGF2 α . Cloprostenol is a functional synthetic analogue of the naturally occurring PGF2 α dinoprost. ACTIONS In the reproductive system PGs play a role in ovulation, luteolysis, gamete transport, uterine motility, expulsion of foetal membranes, and sperm transport in both the male and female tracts. PGs are employed in reproductive therapeutics primarily for their potent luteolytic effects. PGF2 α causes rapid regression of functional corpora lutea, with resultant rapid decline in progesterone production. Luteolysis is usually followed by ovarian follicular development and a return to oestrus with normal ovulation. In cattle oestrus occurs 2 - 4 days after luteolysis. The early corpus luteum is insensitive to the effects of PG; this refractory period spans the first 4 - 5 days post ovulation in cows. The precise mechanism of PG-induced luteolysis is uncertain but may relate to blood flow changes in the uteroovarian vessels, inhibition of the normal ovarian response to circulating gonadotrophin, or stimulation of catalytic enzymes. PGF2 α also has a direct stimulatory effect on uterine Lesen Sie das vollständige Dokument
PAGE 1 OF 2 MATERIAL SAFETY DATA SHEET: 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING PRODUCT NAME : Estroplan flexi OTHER NAMES : Estroplan, Cloprostenol Injection RECOMMENDED USE: FOR ANIMAL TREATMENT ONLY. Luteolysis of functional corpora lutea in cows. MANUFACTURER COMPANY DETAILS: LICENSEE (NEW ZEALAND) DETAILS: Parnell Manufacturing Pty Ltd Parnell NZ Co ADDRESS ADDRESS Unit 4, Century Estate PO Box 73160 476 Gardeners Road Auckland International Airport Alexandria, NSW 2015 Manukau 2150 Australia New Zealand TELEPHONE NUMBER TELEPHONE NUMBER 61 (0)2-9667 4411 0800 446 282 (Toll free within NZ) EMERGENCY TELEPHONE NUMBER EMERGENCY TELEPHONE NUMBER 61 (0)2-9667 4411 (Business Hours) 0800 446 282 (Business Hours) FACSIMILE NUMBER FACSIMILE NUMBER 61 (0)2-9667 4139 0800 727 533 (Toll free within NZ) 2. HAZARDS IDENTIFICATION Hazardous substance according to criteria of Worksafe Australia. 3. COMPOSITION/INFORMATION ON INGREDIENTS CHEMICAL ENTITY CAS NUMBER PROPORTION Buffering Agents <1% w/v Cloprostenol (as sodium) 55028-72-3 0.025% w/v Preservative <1% w/v Water 7732-18-5 to 100% 4. FIRST AID MEASURES Wash off any _Estroplan _contacting skin immediately using soap and water. Seek medical assistance if required. SWALLOWED: Seek medical assistance if required. EYE: If in eyes, hold eyes open, flood with water for at least 15 minutes. Seek medical assistance if required. SKIN: If skin contact occurs remove contaminated clothing and wash skin thoroughly with soap and water. Seek medical assistance if required. INHALED: Seek medical assistance if required. FIRST AID FACILITIES: No specific first aid facilities required. ADVICE TO DOCTOR: Treat symptomatically as required. 5. FIRE-FIGHTING MEASURES This material is not considered a fire hazard. Use standard fire fighting techniques to extinguish fires involving this material. Use water spray, dry chemical, carbon dioxide or foam. 6. ACCIDENTAL RELEASE MEASURES Clear immediate area of unprotected personnel. Clean up spilled material Lesen Sie das vollständige Dokument