VITAMIN D CAPSULE

Země: Kanada

Jazyk: angličtina

Zdroj: Health Canada

Aktivní složka:

VITAMIN D3

Dostupné s:

JAMP PHARMA CORPORATION

ATC kód:

A11CC05

INN (Mezinárodní Name):

COLECALCIFEROL

Dávkování:

2000UNIT

Léková forma:

CAPSULE

Složení:

VITAMIN D3 2000UNIT

Podání:

ORAL

Jednotky v balení:

100

Druh předpisu:

Prescription

Terapeutické oblasti:

VITAMIN D

Přehled produktů:

Active ingredient group (AIG) number: 0108524011; AHFS:

Stav Autorizace:

APPROVED

Datum autorizace:

2020-09-14

Charakteristika produktu

1
PRESCRIBING INFORMATION
PR VITAMIN D
CHOLECALCIFEROL CAPSULES, MFR. STD.
2000 IU
VITAMIN D PRODUCT
PREPARED BY:
Date of Preparation:
September 14, 2020
JAMP Pharma Corporation
1310 rue Nobel
Boucherville QC
J4B 5H3
SUBMISSION CONTROL NUMBER: 240944
2
PRESCRIBING INFORMATION
PR
VITAMIN D
Cholecalciferol Capsules, Mfr. Std.
2000 IU
THERAPEUTIC CLASSIFICATION
Vitamin D Product
PHARMACOLOGY
Vitamin D is a fat-soluble vitamin that helps regulate serum calcium
and phosphorous
concentrations by enhancing the efficiency of the small intestine to
absorb these minerals from
the diet. Vitamin D has two main forms: cholecalciferol (Vitamin D
3
), and ergocalciferol
(Vitamin D
2
).
In humans, cholecalciferol is synthesized in the skin from
7-dehydrocholesterol on exposure to
ultraviolet radiation and obtained from the diet from fish liver oils
and salt water fish. In the
absence of adequate sunlight exposure, vitamin D
3
is an essential dietary nutrient.
Cholecalciferol is a prohormone with several active metabolites that
act as hormones. Vitamin D
is metabolised by the liver to form 25-hydroxycholecalciferol
(calcifediol), which is then
converted in the kidneys to the active Vitamin D hormone,
1,25-dihydroxyvitamin D
3
(calcitriol).
In its biologically active form vitamin D
3
stimulates intestinal calcium absorption, incorporation
of calcium into the osteoid, and release of calcium from bone tissue.
In the small intestine it
promotes rapid and delayed calcium uptake. The passive and active
transport of phosphate is
also stimulated. In the kidney, it inhibits the excretion of calcium
and phosphate by promoting
tubular resorption. The production of parathyroid hormone (PTH) in the
parathyroids is
inhibited directly by the biologically active form of vitamin D
3
. PTH secretion is inhibited
further by the increased calcium uptake in the small intestine under
the influence of biologically
active vitamin D
3
.
PHARMACOKINETICS
Vitamin D from nutritional sources and its analogues are readily
absorbed from the small
intestine in