TP-Mecotil 300 Sol Tilmicosin Phosphate 300mgml Solution

Země: Malajsie

Jazyk: angličtina

Zdroj: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktivní složka:

TILMICOSIN PHOSPHATE

Dostupné s:

Thye Pharma Sdn. Bhd

INN (Mezinárodní Name):

TILMICOSIN PHOSPHATE

Jednotky v balení:

250ml mL

Výrobce:

THYE PHARMA SDN. BHD.

Charakteristika produktu

Veterinary Package Insert
TP-MECOTIL
300
SOL
TILMICOSIN
PHOSPHATE 300MG/ML SOLUTION
PRODUCT DESCRIPTION
Light brown to brown colour liquid, which contains
30% of tilmicosin phosphate in 250ml bottle.
PHARMACODYNAMICS & PHARMACOKINETICS
Tilmicosin is a mainly bactericidal semi-synthetic
antibiotic of the macrolide group. It is believed to
affect bacterial protein synthesis.
Tilmicosin has a wide spectrum of activity against
Gram-positive organisms and is particularly active
against
Pasteurella, Actinobacillus (Haemophilus)
and Mycoplasma organisms of bovine, porcine and
avian origin. Tilmicosin has some activity against
certain
Gram-negative
micro-organisms.
Cross
resistance between tilmicosin and other macrolide
antibiotics has been observed.
When administered orally to chickens, turkeys and
pigs with drinking water and to calves with milk
replacer, tilmicosin is absorbed and moves rapidly
out of the serum into areas of low pH. This results
in very low serum concentrations, but detectable
levels of tilmicosin are found in lung tissue as early
as 6 hours after starting the treatment. In chicken
or turkeys, tilmicosin is also detected in pooled air
sac tissue as early as 6 hours after starting the
treatment.
It
is
also
known
that
tilmicosin
is
concentrated in alveolar macrophages of swine.
When administered orally to calves tilmicosin is
detected in lungs after 6 hours and remains at the
therapeutic level up to 60 hours from the last dose.
INDICATION
_Pigs: _
For the treatment
and prevention of respiratory
infections
associated
with
Mycoplasma
hyopneumoniae,
Pasteurella
multocida
and
Actinobacillus pleuropneumoniae when the disease
has been diagnosed at the herd level.
_Chickens (broilers and pullets): _
For the treatment
and prevention of respiratory
infections
in
poultry
flocks
associated
with
Mycoplasma
gallisepticum
and
Mycoplasma
synoviae when the disease has been diagnosed at
the herd level.
_Turkeys: _
For the treatment and
prevention of respiratory
infections
in
turkey
flocks
associated
with
Mycoplasma
gall