MIRTAZAPINE ARW mirtazapine 30 mg tablet blister pack

Země: Austrálie

Jazyk: angličtina

Zdroj: Department of Health (Therapeutic Goods Administration)

Aktivní složka:

mirtazapine

Dostupné s:

Arrow Pharma Pty Ltd

INN (Mezinárodní Name):

Mirtazapine

Stav Autorizace:

Registered

Informace pro uživatele

MIRTANZA MIRTAZAPINE
1
MIRTANZA MIRTAZAPINE
_Contains the active ingredient mirtazapine _
CONSUMER MEDICINE INFORMATION
_FOR A COPY OF A LARGE PRINT LEAFLET, PH: 1800 195 055 _
WHAT IS IN THIS LEAFLET
READ THIS LEAFLET CAREFULLY BEFORE
TAKING YOUR MEDICINE.
This leaflet answers some common
questions about mirtazapine. It does
not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
The information in this leaflet was
last updated on the date listed on the
last page. More recent information on
this medicine may be available.
ASK YOUR DOCTOR OR PHARMACIST:
•
if there is anything you do not
understand in this leaflet,
•
if you are worried about taking
your medicine, or
•
to obtain the most up-to-date
information.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using this medicine
against the benefits they expect it
will have for you.
Pharmaceutical companies cannot
give you medical advice or an
individual diagnosis.
Keep this leaflet with your medicine.
You may want to read it again.
WHAT THIS MEDICINE IS
USED FOR
The name of your medicine is
Mirtanza Mirtazapine. It contains the
active ingredient mirtazapine.
It is used to treat and prevent
reoccurrence of depression.
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed this
medicine for another reason.
This medicine is available only with
a doctor's prescription.
_HOW IT WORKS _
Depression is longer lasting or more
severe than the "low moods"
everyone has from time to time due
to the stress of everyday life. It is
thought to be caused by a chemical
imbalance in parts of the brain. This
affects your whole body and can
cause emotional and physical
symptoms, such as feeling low in
spirit, loss of interest in activities,
unable to enjoy life, poor appetite or
overeating, disturbed sleep, often
waking up early, loss of sex drive,
lack of energy and feeling guilty over
nothing. Mirtazapine corrects this
che

Charakteristika produktu

Product Information – Australia
MIRTANZA Mirtazapine Tablets
Page 1
MIRTANZA MIRTAZAPINE TABLETS
NAME OF THE MEDICINE
Mirtazapine
Chemical Name:
(±)-1,2,3,4,10,14b-hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benz-
azepine.
Structural Formula:
Molecular Formula:
C
17
H
19
N
3
Molecular Weight:
265.36
CAS Registry Number:
61337-67-5
DESCRIPTION
Mirtazapine is a tetracyclic piperazinoazepine analogue of mianserin,
a chemical structure unrelated to
tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs) or
selective serotonin reuptake inhibitors.
Mirtazapine is a white to creamy white crystalline powder which is
slightly soluble in water.
Each mirtazapine tablet contains mirtazapine as the active ingredient.
In addition, each tablet contains
the
following
inactive
ingredients:
lactose,
cellulose
microcrystalline,
croscarmellose
sodium,
magnesium stearate, hypromellose, hyprolose , macrogol 8000, titanium
dioxide, iron oxide yellow CI
77492 (15 mg and 30 mg), iron oxide red CI 77491 (30 mg only).
PHARMACOLOGY
PHARMACOLOGICAL ACTIONS
Mirtazapine is an antidepressant, which can be given as treatment for
episodes of major depression.
Mirtazapine is an antagonist of central α
2
-auto and hetero-adrenoceptors which causes an increase in
both noradrenaline and serotonin release. The effect of released
serotonin is exerted specifically via
5-HT
1
type
receptors,
because
5-HT
2
and
5-HT
3
type
receptors
are
specifically
blocked
by
mirtazapine. Mirtazapine is accordingly a noradrenergic and specific
serotonergic antidepressant.
The
α
2
,
5-HT
2
and
5-HT
3
antagonistic
effects
all
contribute
to
the
antidepressant
profile
of
mirtazapine. The presentation of mirtazapine is as a racemate. The two
enantiomers contribute
differently to its pharmacological profile. The α
2
and 5-HT
2
receptor blocking activity is contained in
the (S)+ enantiomer, whereas the 5-HT
3
receptor blocking activity is contained in the (R)- enantiomer.
The presence of both enantiomers is therefore considered to be
essential for the antide