দেশ: অস্ট্রেলিয়া
ভাষা: ইংরেজি
সূত্র: Department of Health (Therapeutic Goods Administration)
Sertraline hydrochloride
Aspen Pharma Pty Ltd
Medicine Registered
SERTRA- Consumer Medicine Information Page 1 of 5 Sertra sertraline CONSUMER MEDICINE INFORMATION (CMI) WHAT IS IN THIS LEAFLET This leaflet answers some common questions about SERTRA. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking SERTRA against the benefits it is expected to have for you. ASK YOUR DOCTOR OR PHARMACIST IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT SERTRA IS USED FOR SERTRA is used to treat depression and conditions called obsessive compulsive disorder (OCD), panic disorder, social phobia (social anxiety disorder) and premenstrual dysphoric disorder (PMDD) PMDD affects some women in the days before their period. PMDD is different from premenstrual syndrome (PMS). The mood symptoms (anger, sadness, tension, etc) in PMDD are more severe than in PMS and affect the woman’s daily activities and relationships with others. SERTRA belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). They are thought to work by blocking the uptake of a chemical called serotonin into nerve cells in the brain. Serotonin and other chemicals called amines are involved in controlling mood. Your doctor, however, may prescribe SERTRA for another purpose. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU. SERTRA should not be used in children and adolescents under the age of 18 years for the treatment of any medical condition other than obsessive compulsive disorder (OCD). The safety and efficacy সম্পূর্ণ নথি পড়ুন
SERTRA- Product Information Page 1 of 20 Sertra PRODUCT INFORMATION NAME OF THE MEDICINE Sertraline (as hydrochloride) is an antidepressant for oral administration. It is chemically unrelated to tricyclic, tetracyclic or other available antidepressant agents. The chemical name for sertraline hydrochloride is (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride. Its structural formula is: C 17 H 17 Cl 2 N.HCl Molecular weight: 342.7 Cas No.: 79559-97-0 DESCRIPTION Sertraline hydrochloride is a white crystalline powder that is slightly soluble in water and isopropyl alcohol and sparingly soluble in ethanol. Sertra tablets come in two strengths and contain either 50 mg or 100 mg of sertraline (as the hydrochloride). The tablets also contain the following excipients: microcrystalline cellulose, calcium hydrogen phosphate, hydroxypropylcellulose, sodium starch glycollate, magnesium stearate, Opadry White YS-1R-7003 and Opadry Clear YS-1R-7006. The tablets are gluten free. PHARMACOLOGY PHARMACODYNAMICS The mechanism of action of sertraline is presumed to be linked to its inhibition of central nervous system neuronal uptake of serotonin (5HT). Studies at clinically relevant doses in humans have demonstrated that sertraline blocks the uptake of serotonin into human platelets. In vitro studies have also suggested that sertraline is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on noradrenaline and dopamine neuronal reuptake. In vitro studies have shown that sertraline has no significant affinity for adrenergic (alpha 1 , alpha 2 , সম্পূর্ণ নথি পড়ুন