FUROSEMIDE tablet

Country: মার্কিন যুক্তরাষ্ট্র

ভাষা: ইংরেজি

সূত্র: NLM (National Library of Medicine)

সক্রিয় উপাদান:

FUROSEMIDE (UNII: 7LXU5N7ZO5) (FUROSEMIDE - UNII:7LXU5N7ZO5)

থেকে পাওয়া:

MWI/VetOne

INN (International Name):

FUROSEMIDE

রচনা:

FUROSEMIDE 12.5 mg

প্রশাসন রুট:

ORAL

প্রেসক্রিপশন টাইপ:

PRESCRIPTION

থেরাপিউটিক ইঙ্গিত:

Dogs - Furosemide Tablets are indicated for the treatment of edema (pulmonary congestion, ascites) associated with cardiac insufficiency and acute non-inflammatory tissue edema. In cases of edema involving cardiac insufficiency, the continued use of heart stimulants such as digitalis or its glycosides is indicated. The rationale for efficacious use of diuretic therapy is determined by the clinical pathology producing the edema. Animal reproductive studies have shown that furosemide may cause fetal abnormality and the drug is contraindicated in pregnant animals. Furosemide is contraindicated in anuria, furosemide hypersensitivity, hepatic coma, or during electrolytic imbalances. Monitor serum electrolytes, BUN and CO2 frequently. Monitor serum potassium levels and watch for signs of hypocalcemia. Corticosteroids cause an additive potassium-depletion effect.

পণ্য সারাংশ:

Furosemide Tablets are available in 12.5 mg and 50 mg strength and supplied in bottles containing 500 tablets. NDC 13985-586-12 - 12.5 mg – 500 tablets NDC 13985-585-50 - 50 mg – 500 tablets

অনুমোদন অবস্থা:

New Animal Drug Application

পণ্য বৈশিষ্ট্য

FUROSEMIDE- FUROSEMIDE TABLET
MWI/VETONE
----------
FUROSEMIDE TABLETS
Approved by FDA under NADA # 129-034
Furosemide is not USP for dissolution.
For use in dogs only.
CAUTION:
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION:
Furosemide is a potent loop diuretic which is a derivative of
anthranilic acid. The
structure is:
CHEMICAL NAME: 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid.
Furosemide is pharmacodynamically characterized by the following:
1) It is administered orally. It is easily absorbed from the
intestinal tract and begins to
act in 30 to 60 minutes after oral administration.
2) Is a loop diuretic which inhibits reabsorption of sodium and
chloride at the ascending
loop of Henle in the kidneys, enhancing water excretion.
3) A dose-response relationship and a ratio of minimum to maximum
effective dose
range greater than tenfold.
4) A high degree of efficacy, low inherent toxicity and a high
therapeutic index.
ACTIONS:
The therapeutic efficacy of Furosemide Tablets is from the activity of
the intact and
unaltered molecule throughout the nephron, inhibiting the reabsorption
of sodium not
only in the proximal and distal tubule but also in the ascending limb
of the loop of Henle.
The prompt onset of action is a result of the drug's rapid absorption
and a poor lipid
solubility. The low lipid solubility and a rapid renal excretion
minimize the possibility of its
1, 2
3
1
solubility. The low lipid solubility and a rapid renal excretion
minimize the possibility of its
accumulation in tissues and organs or crystalluria. Furosemide Tablets
have no inhibitory
effect on carbonic anhydrase or aldosterone activity in the distal
tubule. The drug
possesses diuretic activity either in the presence of acidosis or
alkalosis.
INDICATIONS:
Dogs - Furosemide Tablets are indicated for the treatment of edema
(pulmonary
congestion, ascites) associated with cardiac insufficiency and acute
non-inflammatory
tissue edema. In cases of edema involving cardiac insufficiency, the
con