OXITETRACICLINA 200mgml L.A. Solution for Injection

Страна: Малайзия

Език: английски

Източник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активна съставка:

OXYTETRACYCLINE DIHYDRATE

Предлага се от:

Taseen Trading Sdn Bhd

INN (Международно Name):

OXYTETRACYCLINE DIHYDRATE

Броя в опаковка:

100.00 mcg/mL

Произведено от:

Industrial Veterinaria, S.A. (INVESA)

Данни за продукта

PACKAGE INSERT
BRAND OR PRODUCT NAME
OXITETRACICLINA 200mg/ml L.A. Solution for Injection
Oxytetracycline
NAME AND STRENGTH OF ACTIVE SUBSTANCE(S)
Oxytetracycline Dihydrate 215.6mg/ml
PRODUCT DESCRIPTION
A transparent, yellow, slightly dense and viscous solution.
PHARMACODYNAMICS
Oxytetracycline is a bacteriostatic antibiotic that inhibits protein
synthesis in susceptible bacteria.
Inside the cell it binds irreversibly to receptors on the 30S subunit
of the bacterial ribosome where it
interferes with the binding of the aminoacyl-transfer RNA to the
acceptor site on the messenger RNA
ribosome complex. This effectively prevents the addition of amino
acids to the elongating peptide
chain, inhibiting protein synthesis. The product is specifically
formulated to provide a prolonged action
resulting in sustained antibacterial activity. Oxytetracycline had
been shown to be effective in vitro
against the following bacterial species: Bordetella bronchiseptica,
Corynebacterium pyogenes,
Erysipelothrix rhusiopathiae, Escherichia coli, Haemophilus somnus,
Pasteurella haemolytica,
Pasteurella multocida, Salmonella dublin, Staphylococcus aureus,
Streptococcus agalactiae,
Streptococcus faecalis, Streptococcus pyogenes and Streptococcus
uberis.
PHARMACOKINETICS
Blood levels persist for at least 4 days after administration by the
intramuscular route. Maximum
blood levels are achieved between 4 and 8 hours following
intramuscular administration.
ENVIRONMENTAL PROPERTIES
not relevant
INDICATION
The product is indicated for use in cattle, sheep and pigs in the
treatment of: - Atrophic rhinitis caused
by Bordetella bronchiseptica, Mannheimia haemolytica and Pasteurella
multocida. - Navel/joint ill
caused by Arcanobacterium pyogenes, E. coli or Staphylococcus aureus.
- Mastits caused by
Corynebacterium pyogenes, E. coli, Staphylococcus aureus,
Streptococcus agalactiae or Streptococcus
uberis. - Metritis caused by E. coli or Streptococcus pyogenes. -
Pasteurellosis and infections of the
respiratory tract caused by Mannheimia haemolytica