Страна: Ирландия
Език: английски
Източник: HPRA (Health Products Regulatory Authority)
GLYCOPROTEIN E DEFICIENT (GE) BOVINE HERPES VIRUS TYPE 1 (BHV-1)STRAIN GK/D LIVE
Intervet Ireland Limited
QI02AD01
GLYCOPROTEIN E DEFICIENT (GE) BOVINE HERPES VIRUS TYPE 1 (BHV-1)STRAIN GK/D LIVE
Unknown
Lyophilisate and solvent for suspension for injection
POM(E)
Bovine
Bovine rhinotracheitis virus vaccine (IBR)
Immunological - Live Vaccine
Authorised
2002-10-24
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE VETERINARY MEDICINAL PRODUCT Bovilis IBR marker live, lyophilisate and solvent for suspension for cattle 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Per dose of 2 ml reconstituted vaccine: ACTIVE SUBSTANCE(S) BHV-1, strain GK/D (gE¯ ): 10 5.7 - 10 7.3 TCID 50 *. *TCID 50 : tissue culture infective doses 50% For the full list of excipients, see section 6.1. 3 PHARMACEUTICAL FORM Lyophilisate and solvent for suspension. Lyophilisate: off-white to light pink-coloured pellet. Solvent: colourless solution 4 CLINICAL PARTICULARS 4.1 TARGET SPECIES Cattle HEALTH PRODUCTS REGULATORY AUTHORITY ________________________________________________________________________________________________________________________ _Date Printed 03/11/2014_ _CRN 7018812_ _page number: 1_ 4.2 INDICATIONS FOR USE, SPECIFYING THE TARGET SPECIES Active immunisation of cattle to reduce the intensity and duration of the clinical respiratory signs induced by an infection with BHV-1 and to reduce nasal excretion of field virus. Onset of immunity: An increase in immunity was demonstrated 4 days after intranasal vaccination and 14 days after intramuscular vaccination of 3 month old seronegative animals. Duration of immunity: After intranasal administration to 2 week old calves without maternal antibodies, immunity lasts at least until the age of 3-4 months, when the animals should be revaccinated. In the presence of maternally derived antibodies, the protection of the vaccine may not be complete until this revaccination. Revaccination at 3-4 months of age results in protective immunity that lasts for at least 6 months. Single intranasal or intramuscular vaccination of 3 month old animals provides protective immunity (reduction of clinical signs and reduction of viral excretion), which was demonstrate Прочетете целия документ