البلد: ماليزيا
اللغة: الإنجليزية
المصدر: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CINNARIZINE
PRIME PHARMACEUTICAL SDN. BHD.
CINNARIZINE
1000 Tablets; 1000 Tablets
PRIME PHARMACEUTICAL SDN. BHD.
Consumer Medication Information Leaflet(RiMUP) PRINAZIN TABLET 25MG Cinnarizine (25mg ) 1 What is in this leaflet 1. What Prinazin is used for 2. How Prinazin work s 3. Before you use Prinazin 4. How to use Prinazin 5. While you are using it 6. Side effects 7. Storage and Disposal of Prinazin 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision What Prinazin is used for Maintenance treatment for d isorders of balance -labyrinthine (internal ear disturbances )including vertigo (spinning feeling), dizziness, tinnitus (ringing of ears) , nystag mus (involuntary eye mov ement) , nausea and vomiting. It is also used as prevention of motion sickness. How Prinazin work s Cinnarizine has antihistamine activity , relaxes the smooth muscle sand dilates blood vessels . Before you use Prinazin -When you m ust not use it Ifyou are allergic to cinnarizine or any of the other ingredients of Prinazin . -Before you start to use it Caution when driving or doing jobs requiring alertness because of possible drowsiness. -Taking other medic ine s Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. How to use Prinazin -How much to use Disorders of balance: Adult: 1 tablet of 25 mg three times a day . Prevention of motion sickness: Adult and adolescent aged 13 years and above: 1 tablet of 25 mg at least half an hour before travelling; to be repeated every 6 hours; Children aged 6 to 12 years: half of the adult dose i s recommended. Cinnarizine should preferably be taken after meals. It is for oral administration. Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet. If you do not understand the instructions on the label, ask your doctor or pharmacist for help. -When to use it Use as directed by your doctor or pharmacist. -How long to use it Continue taking Prinazin for as long as your doctor recom mends. -If you اقرأ الوثيقة كاملة
PRINAZIN TABLET 25MG Description: White, round, flat with top -scored tablet. Diameter = 7.00mm. CONTENT Cinnarizine 25mg/tablet INDICATIONS - Disorders of balance - maintenance therapy for symptoms of labyrinthine disorders, including vertigo, dizziness, tinnitus, nystagmus, nausea and vomiting. - Prophylaxis of motion sickness. PHARMACOLOGY Cinnarizine has antihistamine activity and is also a smooth muscle relaxant and vasodilator. Sedative effects are not marked. It is well absorbed orally, metabolised in the liver, and excreted in the urine. ADVERSE EFFECTS Allergic skin reactions , fatigue , drowsiness and dyskinesia , extrapyramidal disorder , Parkinsonism and tremor in elderly people during prolonged therapy . DRUG INTERACTION S Alcohol, CNS depressants and tricyclic antidepressants - The sedative effects of cinnarizine and of any of the following may be potentiated when used concomitantly. Diagnostic interference - Because of its antihistamine effect, cinnarizine may prevent otherwise positive reactions to dermal reactivity indicators if used up to 4 days p rior to skin testing. PRECAUTIONS - As with other antihistamines cinna rizine may cause epigastric distress; taking it after meals may diminish gastric irritation. - In patients with Parkinson’s disease cinnarizine should only be given if the advantages outweigh the possible risk of aggravating this disease. - Cinnarizine may cause somnolence, especially at the start of treatment. Therefore, caution should be taken when alcohol, central nervous system (CNS) depressants or tricyclic antidepressants are used concomitantly. PREGNANCY AND LACTAT ION Safety for use in pregnancy and lactation has not been established. Pregnancy: Although in animal studies, cinnarizine has shown no teratogenic effects, as with all drugs, cinnarizine should be used during pregnanc y only if the therapeutic benefits justify the potential risks for the fetus. Breast -feeding: There are no data on the excretion of cinnarizine in human breast milk: nursing should therefore be di اقرأ الوثيقة كاملة