国家: 加拿大
语言: 英文
来源: Health Canada
CLOBETASOL PROPIONATE
TARO PHARMACEUTICALS INC
D07AD01
CLOBETASOL
0.05%
CREAM
CLOBETASOL PROPIONATE 0.05%
TOPICAL
50 GM
Prescription
ANTI-INFLAMMATORY AGENTS
Active ingredient group (AIG) number: 0110995001; AHFS:
APPROVED
2005-09-20
PRESCRIBING INFORMATION PR TARO-CLOBETASOL CLOBETASOL PROPIONATE CREAM USP, 0.05% W/W PR TARO-CLOBETASOL CLOBETASOL PROPIONATE OINTMENT USP, 0.05% W/W THERAPEUTIC CLASSIFICATION Topical corticosteroid Taro Pharmaceuticals Inc. Date of Revision: 130 East Drive Brampton, Ontario November 26, 2012 L6T 1C1 Control # 147321 Taro Pharmaceuticals Inc. 1 PRESCRIBING INFORMATION PR TARO-CLOBETASOL CLOBETASOL PROPIONATE CREAM USP, 0.05% W/W PR TARO-CLOBETASOL CLOBETASOL PROPIONATE OINTMENT USP, 0.05% W/W TOPICAL CORTICOSTEROID ACTIONS AND CLINICAL PHARMACOLOGY The corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses, corticosteroids are used primarily for their anti-inflammatory and/or immunosuppressive effects. Topical corticosteroids such as clobetasol propionate are effective in the treatment of corticosteroid-responsive dermatoses primarily because of their anti-inflammatory, anti-pruritic, and vasoconstrictive actions. However, while the physiologic, pharmacologic and clinical effects of the corticosteroids are well known, the exact mechanisms of their actions in each disease are uncertain. Clobetasol propionate has been shown to have topical and systemic pharmacologic and metabolic effects characteristic of the corticosteroid class of drugs. Taro Pharmaceuticals Inc. 2 INDICATIONS AND CLINICAL USE Clobetasol Propionate Cream and Ointment are indicated for the topical therapy of recalcitrant corticosteroid-responsive dermatoses, including severe cases of psoriasis (excluding widespread plaque psoriasis) and eczematous dermatitis. CONTRAINDICATIONS Clobetasol Propionate Cream and Ointment are not indicated for the treatment of rosacea, acne vulgaris, perioral dermatitis or perianal and genital pruritus. These preparations are contraindicated also in the treatment of primary infected bacterial or fungal skin lesions if no anti-infective agent is used simultaneously, in primary cutaneous viral infections (i.e., herpes simpl 阅读完整的文件