SENTINEL FLAVOR TABS 2-10LBS- milbemycin oxime, lufenuron tablet

国家: 美国

语言: 英文

来源: NLM (National Library of Medicine)

有效成分:

MILBEMYCIN OXIME (UNII: 0502PUN0GT) (MILBEMYCIN OXIME - UNII:0502PUN0GT)

可用日期:

Virbac AH, Inc

INN（国际名称）:

MILBEMYCIN OXIME

组成:

MILBEMYCIN OXIME 2.3 mg

给药途径:

oral

处方类型:

PRESCRIPTION

疗效迹象:

SENTINEL FLAVOR TABS are indicated for use in dogs and puppies, four weeks of age and older, and two pounds body weight or greater. SENTINEL FLAVOR TABS are also indicated for the prevention of heartworm disease caused by Dirofilaria immitis for the prevention and control of flea populations, the control of adult Ancylostoma caninum  (hookworm), and the removal and control of adult Toxocara canis and Toxascaris leonina (roundworm) and Trichuris vulpis (whipworm) infections. Lufenuron controls flea populations by preventing the development of flea eggs and does not kill adult fleas. Concurrent use of an adulticide product may be necessary for adequate control of adult fleas. Without concurrent use of an adulticide, adequate flea control may not be achieved in dogs that have repeated exposure to flea infested animals or environments.

產品總結:

SENTINEL FLAVOR TABS are available in four tablet sizes (see Dosage Section) formulated according to the weight of the dog. Each tablet size is available in color-coded packages of 6 or 12 tablets each, which are packaged 10 per display carton.

授权状态:

New Animal Drug Application

产品特点

SENTINEL FLAVOR TABS 2-10LBS- MILBEMYCIN OXIME, LUFENURON TABLET
VIRBAC AH, INC
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SENTINEL® FLAVOR TABS® 2-10LBS
SENTINEL® FLAVOR TABS®
(milbemycin oxime+lufenuron)
The palatable once-a-month prescription tablet that prevents heartworm
disease and flea populations in
dogs and puppies. SENTINEL® (milbemycin oxime/lufenuron) FLAVOR
TABS® also controls flea
populations, adult hookworm infections, remove and controls adult
roundworm and whipworm
infections in dogs and puppies.
CAUTION
Federal (USA) law restricts this drug to use by or on the order of a
licensed veterinarian.
WARNINGS
Not for human use. Keep this and all drugs out of reach of children.
DES CRIPTION
SENTINEL FLAVOR TABS are available in four tablet sizes in color-coded
packages for oral
administration to dogs and puppies according to their weight. (See
Dosage Section). Each tablet is
formulated to provide a minimum of 0.23 mg/pound (0.5 mg/kg) of
milbemycin oxime and 4.55 mg/pound
(10 mg/kg) body weight of lufenuron.
Milbemycin oxime consists of the oxime derivatives of
5-didehydromilbemycins in the ratio of
approximately 80% A (C
H NO , MW 555.71) and 20% A (C
H NO , MW 541.68). Milbemycin
oxime is classified as a macrocyclic anthelmintic.
Lufenuron is a benzoylphenylurea derivative with the following
chemical composition:
N-[2,5-dichloro-4-(1,1,2,3,3,3, -
hexafluoropropoxy)-phenylaminocarbonyl-2,6-difluorobenzamide
(C
H Cl
F N O , MW 551.15). Benzoylphenylurea compounds, including lufenuron,
are classified as
insect development inhibitors (IDIs).
MODE OF ACTION
Milbemycin oxime, one active ingredient in SENTINEL FLAVOR TABS, is a
macrocyclic anthelmintic
which is believed to act by interfering with invertebrate
neurotransmission.
Milbemycin oxime eliminates the tissue stage of heartworm larvae and
the adult stage of hookworm
(_Ancylostoma caninum_), roundworm (_Toxocara canis and Toxascaris
leonina_) and whipworm (_Trichuris_
_vulpis_) infestations when administered orally according to the
recommended dosage schedule.
Lufenuron, the ot