RESINCOLESTIRAMINA POWDER

国家: 新加坡

语言: 英文

来源: HSA (Health Sciences Authority)

有效成分:

CHOLESTYRAMINE RESIN (ANHYDROUS)

可用日期:

ZYFAS PHARMA PTE LTD

ATC代码:

C10AC01

剂量:

4 g/sachet

药物剂型:

POWDER

组成:

CHOLESTYRAMINE RESIN (ANHYDROUS) 4 g/sachet

给药途径:

ORAL

处方类型:

Prescription Only

厂商:

LABORATORIOS RUBIO SA

授权状态:

ACTIVE

授权日期:

1991-09-27

产品特点

RESINCOLESTIRAMINA
Cholestyramine
RESINCOLESTIRAMINA Powder
RESINCOLESTIRAMINA is an insoluble salt of an anionic exchange
resin, with a high capacity for absorption of bile acids in the
intestine.
Bile acids are produced in the liver by cholesterol oxidation.
Due to this fact, when they are absorbed, it becomes necessary to
synthesise them from the body’s cholesterol thereby lowering
cholesterol levels in the body.
In order to increase the drug’s efficacy, a low-cholesterol diet
should be given. Due to the high absorption capacity of
RESINCOLESTIRAMINA for bile acids, it is used in the treatment of
pruritus secondary to obstructive jaundice, both entero- and
extrahepatic.
DESCRIPTION
White sachets of a complex material of polyethylene-aluminium-
polyethylene-paper which contains flavoured powder.
COMPOSITION PER SACHET:
Cholestyramine (anhydrous) 4g
Excipients q.s.
Strawberry flavour
INDICATIONS
RESINCOLESTIRAMINA is indicated as adjunctive therapy in
hypercholesterolaemia and as an adjunct for the relief of
intractable diarrhoea and for the relief of pruritus secondary to
biliary stasis.
CONTRAINDICATIONS
It is contraindicated in patients with complete biliary obstruction
and in those individuals who have shown hypersensitivity to any of
its components.
SIDE-EFFECTS
The most common side-effect of cholestyramine is constipation;
faecal impaction may develop and haemorrhoids may be
aggravated. Other gastro-intestinal side-effects, including
abdominal discomfort or pain, heartburn, flatulence, nausea,
vomiting, and diarrhoea, may also occur.
Cholestyramine in high doses may cause steatorrhoea by
interfering with the absorption of fats from the gastro-intestinal
tract and therefore decreased absorption of fat-soluble vitamins,
such as vitamins A, D, and K, may occur. Chronic administration
of cholestyramine may thus result in an increased bleeding
tendency due to hypoprothrombinaemia associated with vitamin K
deficiency or it may lead to osteoporosis due to impaired calcium
and vitamin D absorption.
Due to the