PREDSOLONE TABLET 5MG

国家: 马来西亚

语言: 英文

来源: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

有效成分:

PREDNISOLONE

可用日期:

DYNAPHARM (M) SDN BHD

INN（国际名称）:

PREDNISOLONE

每包单位数:

1000 Tablets; 100 Tablets

厂商:

DYNAPHARM (M) SDN BHD

资料单张

Consumer Medication Information Leaflet (RiMUP)
PREDSOLONE TABLET 5MG
Prednisolone (5mg)
1
What is in this leaflet
1.
What Predsolone Tablet 5mg is used
for
2.
How Predsolone Tablet 5mg works
3.
Before you use Predsolone Tablet
5mg
4.
How to use Predsolone Tablet 5mg
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of Predsolone
Tablet 5mg
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10. Date of revision
What Predsolone Tablet 5mg is used
for
Predsolone Tablet 5mg is used for
conditions that are responsive to this
type of steroid therapy such as asthma,
skin reactions and inflammatory bowel
disease.
How Predsolone Tablet 5mg works
Prednisolone has anti-inflammatory
action, anti-allergic, anti-shock (sudden
drop of blood flow) and act to suppress
or prevent the immune response.
Before you use Predsolone Tablet 5mg
- When you must not use it
Do not use Predsolone Tablet 5mg if
you have:
- Fragile bones
- Active ulcer or mental disorder
- Infections unless effective with
specific concurrent medicines
- Undergoing immunisations.
Pregnancy and lactation
Do not take Predsolone Tablet 5mg if
you are pregnant, trying to get pregnant
or think you may be pregnant.
Do not take Predsolone Tablet 5mg if
you are breast-feeding. Ask your doctor
or pharmacist for advice before taking
any medicine.
Some medicines may increase the
effects of Predsolone Tablet 5mg and
your doctor may wish to monitor you
carefully if you are taking these
medicines (including some medicines
for HIV such as cobicistat)
- Before you start use it
Tell your doctor or pharmacist if you
have:
- Diabetes
- Stomach or intestinal ulcer
- Heart disease
- High blood pressure
- High lipid (fats) content in blood
- Underactive thyroid gland
- Muscle weakness
- Kidney function impairment or stones
- Pheochromocytoma (a tumour of the
adrenal gland)
Talk to your doctor before taking
Predsolone Tablet 5mg, if you have:
Systemic sclerosis (an autoimmune
disorder). Taking daily doses of 15mg or
more may increase the risk of a

产品特点

PREDSOLONE TABLET 5MG
MAL19910163AZ
DESCRIPTION:
TABLET
Colour
:
White
Shape
:
Oblong/Flat/Scored
Marking
:
“P5”
EACH TABLET CONTAINS:
Prednisolone ............................................. 5 mg
PHARMACODYNAMICS:
Prednisolone is a synthetic adrenocorticoid hormone. It has
anti-inflammatory action, a weaker sodium-retaining effect than
cortisone in normal dosage, anti-allergic, antishock and
immunosuppressant action. At cellular level, it diffuses across cell
membranes and complexes then enter the cell nucleus, bind to DNA and
stimulate transcription of mRNA and subsequent protein
synthesis of various enzymes thought to be responsible for the
glucocorticoid effects and mineralocorticoid effects.
PHARMACOKINETICS:
Prednisolone is absorbed after oral administration. The biological
half-life is about 3 hours. About 50% is bound to plasma proteins. It
is metabolised by reduction to 20-dihydroprednisolone,
20-dihydroprednisone and hydrocortisone and conjugation occur to some
extent. About 10 to 30% of a dose is excreted in the urine as
unchanged Prednisolone and the remainder as metabolites, 60 to 80% of
which is conjugated; a dose is completely excreted in 3 days.
Prednisolone is excreted in milk in insignificant amounts.
INDICATION:
Corticosteroid indicated conditions include allergic disorders such as
bronchial asthma & allergic skin reactions; blood disorders;
selected collagen & rheumatic disorders; connective tissue disorders;
gastrointestinal disorders such as inflammatory bowel disease,
and also disorders responsive to adrenocortical hormone therapy.
RECOMMENDED DOSE:
Adults
:
5 - 60 mg daily in 2 - 4 divided doses depending on the disease being
treated.
Children :
0.14 - 2 mg/kg body weight in 4 divided doses or 4 - 6 mg/meter square
daily in 4 divided doses.
CONTRAINDICATION:
Osteoporosis; active ulcer, psychoses or severe psychoneuroses.
Systematic fungal infections. Acute infections unless effective,
specific concurrent chemotherapy can be administered. Patients should
not undergo immunisations. Tub