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KENACORT-A 40 – Product Information
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PRODUCT INFORMATION
KENACORT
-A 40 INJECTION
(STERILE TRIAMCINOLONE ACETONIDE SUSPENSION USP)
40 MG IN 1 ML
FOR INTRAMUSCULAR AND INTRA-ARTICULAR OR INTRASYNOVIAL USE
NOT FOR INTRAVENOUS, INTRADERMAL OR INTRAOCULAR USE
NAME OF MEDICINE
KENACORT
–A 40 INJECTION - (Sterile Triamcinolone Acetonide Suspension
USP).
The chemical name for triamcinolone acetonide is 9-Fluoro-11 β, 16α,17,21-terahydroxypregna-
1,4-diene-3,20-dione cyclic 16,17-acetal with acetone.
The structural formula is:
DESCRIPTION
Kenacort-A 40 Injection provides a synthetic glucocorticoid corticosteroid with marked anti-
inflammatory action. Each 1mL of the sterile, aqueous suspension provides 40mg of
triamcinolone acetonide, with 6.6 mg sodium chloride for isotonicity, 15 mg benzyl alcohol as a
preservative, 6.4 mg carmellose sodium, 0.4 mg polysorbate 80 and water for injections. The pH
is adjusted using sodium hydroxide and/or hydrochloric acid. At the time of manufacture, the air
in the container is replaced by nitrogen. Kenacort A40 is suitable for intramuscular, intrarticular
or intrasynovial injection. This formulation is not suitable for intravenous, intradermal or
intraocular use.
ACTIONS
Naturally occurring glucocorticoids (hydrocortisone), which also have salt-retaining properties,
are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs are
primarily used for their potent anti-inflammatory effects in
disorders of many organ systems.
Glucocorticoids cause profound and varied metabolic effects. In addition, they modify the body's
immune responses to diverse stimuli.
KENACORT-A 4
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