IVERMECTIN injection

国家: 美国

语言: 英文

来源: NLM (National Library of Medicine)

有效成分:

IVERMECTIN (UNII: 8883YP2R6D) (IVERMECTIN - UNII:8883YP2R6D)

可用日期:

Durvet Inc.

给药途径:

SUBCUTANEOUS

处方类型:

OTC

疗效迹象:

Cattle :  IVERMECTIN Injection is indicated for the effective treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, grubs, sucking lice and mange mites in cattle: Gastrointestinal Roundworms (adults and fourth-stage larvae): Ostertagia ostertagi     (Including inhibited O. ostertagi ) O. lyrata Haemonchus placei Trichostrongylus axei T. colubriformis Cooperia oncophora C. punctata C. pectinata Oesophagostomum radiatum Bunostomum phlebotomum Nematodirus helvetianus (adults only) N. spathiger (adults only) Lungworms (adults and fourth-stage larvae): Dictyocaulus viviparus Cattle Grubs (parasitic stages): Hypoderma bovis H. lineatum Sucking Lice : Linognathus vituli Haematopinus eurysternus Solenopotes capillatus Mites Iscabies: Psoroptes ovis     (Syn.P. communis var.bovis ) Sarcoptes scabiei var. bovis Persistent Activity IVERMECTIN Injection has been proved to effectively control infections and to protect cattle from reinfect

產品總結:

50 mL, 200 mL, 500 mL

授权状态:

Abbreviated New Animal Drug Application

产品特点

IVERMECTIN- IVERMECTIN INJECTION
DURVET INC.
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IVERMECTIN INJECTION
APPROVE BY FDA UNDER ANADA # 200-429
FOR CATTLE AND SWINE
1% STERILE SOLUTION
A PARASITICIDE FOR THE TREATMENT AND CONTROL OF INTERNAL AND EXTERNAL
PARASITES OF CATTLE AND
SWINE
CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT,
AND CONTROL OF PARASITISM.
INTRODUCTION
Ivermectin is an injectable parasiticide for cattle and swine. One
low-volume dose effectively treats and
controls the following internal and external parasites that may impair
the health of cattle and swine:
gastrointestinal roundworms (including inhibited _Ostertagia
ostertagi_ in cattle), lungworms, grubs, sucking
lice, and mange mites of cattle; and gastrointestinal roundworms,
lungworms, lice, and mange mites in swine.
PRODUCT DESCRIPTION
Ivermectin is derived from the avermectins, a family of potent,
broad-spectrum antiparasitic agents isolated
from fermentation of_ Streptomyces avermitilis._
IVERMECTIN Injection is a clear, ready-to-use, sterile solution
containing 1% ivermectin, 40% glycerol formal,
and propylene glycol, q.s. ad 100%. IVERMECTIN Injection is formulated
to deliver the recommended dose
level of 200 mcg ivermectin/kilogram of body weight in cattle when
given subcutaneously at the rate of 1
mL/110 lb (50 kg). In Swine, IVERMECTIN Injection is formulated to
deliver the recommended dose level of 300
mcg ivermectin/kilogram body weight when given subcutaneously in the
neck at the rate of 1 mL/75 lbs (33
kg).
MODE OF ACTION
Ivermectin is a member of the macrocyclic lactone class of
endectocides which have a unique mode of action.
Compounds of the class bind selectively and with high affinity to
glutamate-gated chloride ion channels which
occur in invertebrate nerve and muscle cells. This leads to an
increase in the permeability of the cell
membrane to chloride ions with hyperpolarization of the nerve or
muscle cell, resulting in paralysis and death
of the parasite. Compounds of this class may also interact with other
ligand-gated chloride