Idaman Pharma Enalapril Tablet 5mg

国家: 马来西亚

语言: 英文

来源: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

有效成分:

ENALAPRIL MALEATE

可用日期:

IDAMAN PHARMA MANUFACTURING SDN BHD

INN（国际名称）:

ENALAPRIL MALEATE

每包单位数:

3 x 10 Tablets

厂商:

IDAMAN PHARMA MANUFACTURING SDN BHD

资料单张

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
IDAMAN PHARMA ENALAPRIL TABLET 5MG
Enalapril Maleate (5mg)
WHAT IS IN THIS LEAFLET
1.
What Idaman Pharma Enalapril
Tablet is used for
2.
How
Idaman
Pharma
Enalapril
Tablet works
3.
Before you use Idaman Pharma
Enalapril Tablet
4.
How
to
use
Idaman
Pharma
Enalapril Tablet
5.
While
you
are
using
Idaman
Pharma Enalapril Tablet
6.
Side effects
7.
Storage and Disposal of Idaman
Pharma Enalapril Tablet
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of Revision
WHAT IDAMAN PHARMA ENALAPRIL
TABLET IS USED FOR
Idaman Pharma Enalapril Tablet is
used:
•
To treat your hypertension (high
blood
pressure)
or
heart
failure
(weakening of heart function).
•
To slow
the
worsening of heart
failure
•
To
prevent
symptomatic
heart
failure.
•
To prevent the weakening of heart
function
and
to
slow
the
development
of
symptoms
(for
instance,
shortness
of
breath,
tiredness
after
light
physical
activity
such
as
walking
or
swelling of the ankles and feet).
•
To reduce risk of heart attack.
HOW
IDAMAN
PHARMA
ENALAPRIL
TABLET WORKS
Idaman
Pharma
Enalapril
Tablet
works
by
widening
your
blood
vessels to make it easier for the heart
to pump blood to all parts of your
body.
This
helps
to
reduce
high
blood pressure. In many patients with
heart
failure,
Idaman
Pharma
Enalapril Tablet will help the heart to
function better.
BEFORE YOU USE IDAMAN PHARMA
ENALAPRIL TABLET
_-When you must not take it _
Do
not
take
Idaman
Pharma
Enalapril Tablet if you:
•
are
allergic
to
any
of
its
ingredients.
•
Have
previously
been
treated
with a medication in the same
group of drugs (ACE Inhibitors)
and have had an allergic reaction
with swelling of the face, lips,
tongue
and/or
throat
with
difficulty
in
swallowing
or
breathing. You should not take
Idaman Pharma Enalapril Tablet
if you have had these types of
reactions without a known cause
or if you have been diagnosed
with
hereditary
or
idiopathic
angioedema.
•
have diabetes and are taking a
medicine
called
aliskiren
to

产品特点

IDAMAN PHARMA ENALAPRIL TABLET 5MG
PRODUCT DESCRIPTION
Barrel shaped white tablet, with score on one side and plain on the
other side.
EACH TABLET CONTAINS:
Enalapril Maleate 5mg.
PHARMACODYNAMICS
The mechanism of enalapril lowers blood pressure, believed to be
primarily suppression of the renin-angiotensin-aldosterone system,
which plays a major role in the regulation of blood pressure.
Enalapril
are antihypertensive even in patients with low-renin hypertension. The
administration of enalapril to patients with hypertension results in a
reduction of both supine and standing blood pressure without a
significant increase in heart rate.
Symptomatic postural hypotension is infrequent. In some patients, the
development of optimal blood pressure reduction may require several
weeks of therapy. Abrupt withdrawal of enalapril treatment has not
been associated with rapid increase in blood pressure.
Effective inhibition of ACE activity usually occurs 2 to 4 hours after
oral
administration of an individual dose
of
enalapril. Onset of
antihypertensive activity was usually seen at one hour, with peak
reduction
of
blood
pressure
achieved
by
4
to
6
hours
after
administration. The duration of effect is dose related. However, at
recommended doses, antihypertensive and hemodynamic effects have
been shown to be maintained for at least 24 hours.
In patients with essential hypertension, blood pressure reduction was
accompanied by a reduction in peripheral arterial resistance with an
increase in cardiac output and little or no change in heart rate.
Following administration of enalapril, there was an increase in renal
blood flow; glomerular filtration rate was unchanged. There was no
evidence of sodium or water retention. However, in patients with low
pretreatment
glomerular
filtration
rates,
the
rates
were
usually
increased.
In diabetic and nondiabetic patients with renal disease, decreases in
albuminuria and urinary excretion of IgG and total urinary protein
were seen after the administration of enalapril. When given together
with thi