EVITOL 200 MG

国家: 以色列

语言: 英文

来源: Ministry of Health

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产品特点 产品特点 (SPC)
18-08-2016
公众评估报告 公众评估报告 (PAR)
18-08-2016

有效成分:

TOCOPHEROL (VIT E) (AS TOCOPHERYL ACETATE)

可用日期:

TEVA PHARMACEUTICAL INDUSTRIES LTD, ISRAEL

ATC代码:

A11HA03

药物剂型:

TABLETS

组成:

TOCOPHEROL (VIT E) (AS TOCOPHERYL ACETATE) 200 MG

给药途径:

PER OS

处方类型:

Not required

厂商:

TEVA PHARMACEUTICAL INDUSTRIES LTD, ISRAEL

治疗组:

TOCOPHEROL (VIT E)

治疗领域:

TOCOPHEROL (VIT E)

疗效迹象:

For the prevention and treatment of diseases caused by Vitamin E deficiency.

授权日期:

2013-10-31

产品特点

                                Evitol Tablets, 1 4. 2014, RH
"
ע עבקנ הז ןולע טמרופ
"
רשואו קדבנ ונכותו תואירבה דרשמ י
."
רשואמ ןולע
:
31/3/2014
“This leaflet form
at has been determined by the Ministry of Health and the content
thereof has
been checked and approved.” Date of approval: 31/3/2014
EVITOL
®
TABLETS
COMPOSITION
Each tablet contains:
_Active Ingredient _
dl-alpha-Tocopherol acetate 100 mg or 200 mg (Vitamin E)
_Other Ingredients _
Microcrystalline cellulose, silicon dioxide, hydrogenated vegetable
oil, povidone,
gelatin, sucrose
*
, maize starch, sodium alumino-silicate.
*
_Each Evitol 100 mg tablet contains 9.4 mg sucrose_.
_* Each Evitol 100 mg tablet contains 1.74 mg sodium. _
_ _
_*_
_ Each Evitol 200 mg tablet contains 18.8 mg sucrose. _
_* Each Evitol 200 mg tablet contains 3.5 mg sodium. _
_ _
MECHANISM OF ACTION
Vitamin E is a fat-soluble intracellular antioxidant. It plays an
important role in
preventing
oxidation
of
essential
cellular
constituents,
thereby
preventing
the
formation of toxic oxidation products, such as the peroxides formed
from unsaturated
fatty acids. These lipid peroxides are known to damage cell membranes.
Vitamin E deficiency plays a significant role in the pathogenesis of
hemolytic anemia
in premature infants. Its antioxidant property is important for the
maintenance of red
cell viability. It is also quite likely that vitamin E deficiency
predisposes to the
development of retrolental fibroplasia in premature infants exposed to
higher oxygen
tensions than those of the intrauterine environment.
The need of the body for vitamin E is considerably increased by diets
that contain
foods rich in polyunsaturated fatty acids. This explains vitamin E
deficiency in infants
fed
on
formulas
rich
in
such
fatty
acids.
This
deficiency
is
corrected
by
the
administration of vitamin E. In fact, it has been shown that levels of
vitamin E rise
much slower in artificially-fed infants than in those who are
breastfed.
Human atheromatous lesions contain lipid peroxides. F
                                
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