国家: 马来西亚
语言: 英文
来源: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
MOMETASONE FUROATE
ORGANON MALAYSIA SDN. BHD.
MOMETASONE FUROATE
15gm mcg/mL; 5gm mcg/mL
SCHERING-PLOUGH LABO N.V.
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ ELOMET ® OINTMENT Mometasone Furoate (0.1% w/w) 1 Copyright 2021 Organon group of companies. All rights reserved. WHAT IS IN THIS LEAFLET 1. What _ELOMET OINTMENT _ is used for 2. How _ELOMET OINTMENT_ works _3._ _ _ Before you take _ELOMET _ _OINTMENT _ _4._ _ _ How to take _ELOMET _ _OINTMENT _ 5. While you are taking _ELOMET OINTMENT _ 6. Side effects 7. Storage and Disposal of _ELOMET OINTMENT _ 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT _ELOMET OINTMENT _IS USED FOR _ELOMET OINTMENT _ is used to reduce inflammation and itchiness caused by certain skin problems that are corresponsive to corticosteroids. HOW _ELOMET OINTMENT _ WORKS _ELOMET OINTMENT _ is one of a group of medicines called topical corticosteroids Mometasone furoate have anti- inflammatory, anti itching and blood vessel narrowing action. BEFORE YOU USE _ELOMET _ _OINTMENT _ _ _ _- When you must not use it _ If you are allergic (hypersensitive) to mometasone furoate, or to any of the other ingredients of _ELOMET OINTMENT_ . Side effects that may happen with oral or injectable corticosteroids may also occur with topical corticosteroids, especially in infants and children. Ask your doctor or pharmacist if you are not sure. _-_ _ _ _Before you start to use it _ PREGNANCY AND BREAST-FEEDING You should tell your doctor if you are pregnant or breast-feeding, before you start using _ELOMET _ _OINTMENT_ . _-_ _ _ _Taking other medicines _ Tell your doctor or pharmacist if you are using other creams, ointments or lotions or taking any other medicines. This includes any that you get without a prescription from your pharmacy, supermarket or health food shop. HOW TO USE _ELOMET _ _OINTMENT _ _ _ _-_ _ _ _How much to use _ Always use _ELOMET _ _OINTMENT _ exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. A thin layer of _ELOMET _ _OINTMENT _ should be applied to the affected area of skin. _-_ _ _ _Wh 阅读完整的文件
Copyright 2021 Organon group of companies. All rights reserved. 1 LPC-OG0887-MTL-082017 ELOMET® Cream and Ointment 0.1% Brand of mometasone furoate FOR DERMATOLOGICAL USE ONLY DESCRIPTION: Each gram of ELOMET Cream 0.1% contains 1 mg mometasone furoate, white petrolatum, white wax, hydrogenated phosphatidylcholine, hexylene glycol, titanium dioxide, aluminium starch octenylsuccinate, purified water and phosphoric acid to adjust the pH. Each gram of ELOMET Ointment 0.1% contains 1 mg mometasone furoate, hexylene glycol, white wax, propylene glycol stearate, white petrolatum, purified water and phosphoric acid to adjust the pH. ACTION: Mometasone furoate, a synthetic corticosteroid, exhibits anti-inflammatory, antipruritic and vasoconstrictive properties. PHARMACOLOGY: PRE-CLINICAL DATA: PHARMACODYNAMICS The pharmacologic profile of mometasone furoate was determined by standard laboratory methods. Relative to betamethasone valerate, anti-inflammatory activity and anti-psoriatic activity of mometasone furoate was evaluated in mice and guinea pigs, respectively. Hypothalamic-pituitary-adrenal (HPA) axis suppression, thymolysis and skin atrophy were evaluated in mice. In the croton oil assay in mice, mometasone furoate (ED 50 = 0.02μg/ear) was equipotent to betamethasone valerate after single application, and was approximately eight times as potent as betamethasone valerate after five daily applications (ED 50 = 0.002μg/ear/day vs 0.014μg/ear/day). In guinea pigs, mometasone furoate was approximately twice as potent as betamethasone valerate in reducing M. Ovalis-induced epidermal acanthosis after 14 daily applications. Copyright 2021 Organon group of companies. All rights reserved. 2 With respect to other pharmacologic activities commonly associated with corticosteroids, mometasone furoate (ED 50 = 5.3μg/ear/day) was less potent than betametasone valerate (ED 50 = 3.1μg/ear/day) in suppressing the HPA axis in mice after five daily application. In the thymolysis assay, mometasone furoate (ED 50 = 26.6μg/ear/day 阅读完整的文件