AVM-Artrisa Sachet for Oral Solution 1500mg

国家: 马来西亚

语言: 英文

来源: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

有效成分:

Glucosamine Sulfate Sodium Chloride

可用日期:

AV MANUFACTURING SDN.BHD

INN（国际名称）:

Glucosamine Sulfate Sodium Chloride

每包单位数:

5.0g x 14 sachet Sachets; 5.0g x 3 sachet Sachets

厂商:

AV MANUFACTURING SDN.BHD

资料单张

Consumer Medication Information Leaflet (RiMUP)
AVM-ARTRISA
® SACHET FOR ORAL SOLUTION 1500MG
Glucosamine Sulphate 1500 mg
1 | P a g e
WHAT IS IN THIS LEAFLET
1.
What AVM-Artrisa sachet is used
for
2.
How AVM-Artrisa sachet works
3.
Before you use AVM-Artrisa sachet
4.
How to use AVM-Artrisa sachet
5.
While you are using AVM-Artrisa
sachet
6.
Side effects
7.
Storage and disposal
8.
Product description
9.
Manufacturer and product
registration holder
10.
Date of revision
1.
WHAT AVM-ARTRISA SACHET IS USED
FOR?
AVM-Artrisa sachet is used to relieve
osteoarthritis joints problems.
2.
HOW AVM-ARTRISA SACHET WORKS?
It helps to reduce joint pain, swelling
and improves movement of the joints.
3.
BEFORE YOU USE AVM-ARTRISA
SACHET
_-When you must not use it_
If you are allergic to glucosamine or any
of the ingredients in the product.
_-Before you start to use it_
Read carefully the instruction from
your medical provider and this leaflet
to understand how this medication to
be taken.
_-Taking other medicines_
Talk to your doctor or pharmacist if
you
are
taking
some
medicine
to
control the blood glucose.
The effect of warfarin (a drug used to
prevent blood clotting) may increase
during treatment with glucosamine.
Inform your doctor if you are using this
medicine.
Furthermore, you need to inform them
also if you are taking any prescription
or nonprescription medicine, herbal
preparation, or dietary supplement. In
case of concomitant treatment your
doctor may consider to measure the
effect of warfarin in your blood more
frequently.
Tell your doctor or pharmacist if you
have any medical conditions,
especially if any of the following
apply to you:

if you are pregnant, planning to
become pregnant, or breast-feeding

if you have allergies to medicines,
foods, or other substances
4.
HOW TO USE AVM-ARTRISA SACHET?
_How much to use? _
Adults
One sachet to be taken daily before
meal. The entire contents of one sachet
should be fully dissolved in at least
250 ml water (one glass) and drink
immediately.
_-When to use it_
AVM-Art

产品特点

AVM-ARTRISA
® SACHET FOR ORAL SOLUTION 1500 MG
NAME AND STRENGTH OF ACTIVE SUBSTANCE
Glucosamine sulphate sodium chloride 1884mg equivalent to 1500 mg
glucosamine sulphate (derived from seafood)
PRODUCT DESCRIPTION
AVM-Artrisa
®
sachet is a white to off-white powder to be dissolved in water and
forms a clear solution.
PHARMACODYNAMICS
Glucosamine is a natural substance found in chitin, mucoproteins, and
mucopolysaccharides. It is involved in the manufacture of
glycosaminoglycan, which forms cartilage tissue in the body;
glucosamine is also present in tendons and ligaments. Glucosamine
must be synthesised by the body but the ability to do this declines
with age. Glucosamine and its salts have therefore been
advocated in the treatment of rheumatic disorders including
osteoarthritis. Glucosamine also acts to improve the viscosity of
synovial fluid by increasing synovial fluid production, thereby
providing lubricant activity.
PHARMACOKINETICS
_Absorption _
After oral administration, bioavailability is low due to first-pass
hepatic metabolism~26%
The gastrointestinal absorption is close to 90%
_Distribution _
Glucosamine is not protein-bound, but rather incorporates into plasma
proteins (primarily globulins), Volume of Distribution: 2.5
liters
_Metabolism _
-Liver, extensive
The first-pass effect in the liver in which more than 70% of
glucosamine is metabolized.
_Excretion _
Renal Excretion, 10%; feces, 11%
Part of a dose of glucosamine sulphate is eliminated as carbon dioxide
via expired air
INDICATION
Adjuvant therapy for osteoarthritis
RECOMMENDED DOSAGE
Adults
One sachet to be taken daily before meal. The entire contents of one
sachet should be fully dissolved in at least 250 ml water (one
glass) and drink immediately.
MODE OF ADMINISTRATION
Oral
CONTRAINDICATIONS
Hypersensitivity to glucosamine or to any of the excipients.
As the active ingredient is obtained from seafood (shellfish), the
product should not be given to patients who are allergic to
seafood (shellfish).
WARNINGS AND PRECAUTIONS
-Glucosamine treat