国家: 澳大利亚
语言: 英文
来源: Department of Health (Therapeutic Goods Administration)
cefazolin sodium, Quantity: 524 mg
Strides Pharma Science Pty Ltd
cefazolin sodium
Injection, powder for
Excipient Ingredients:
Intramuscular, Intravenous
1, 10, 5
(S4) Prescription Only Medicine
Cefazolin is indicated in the treatment of the following serious infections due to susceptible organisms:,Respiratory tract infections due to S. pneumoniae, Klebsiella species, H. influenzae, Staph. aureus (penicillin-sensitive and penicillin- resistant), and Group A beta-haemolytic streptococci.,Injectable benzathine penicillin is considered to be the drug of choice in the treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever.,Cefazolin is effective in the eradication of streptococci from the nasopharynx; however, data establishing the efficacy of Cefazolin in the subsequent prevention of rheumatic fever are not available at present.,Genitourinary tract infections due to Esch. coli, Pr. mirabilis, Klebsiella species, and some strains of Enterobacter and enterococci.,Skin and skin structure infections due to Staph. aureus (penicillin-sensitive and penicillin- resistant), and Group A beta-haemolytic streptococci and other strains of streptococci.,Bone and joint infections due to Staph. aureus.,Septicaemia due to S. pneumoniae, Staph. aureus (penicillin-sensitive and penicillin-resistant), Pr. mirabilis, Esch. coli and Klebsiella species.,Endocarditis due to Staph. aureus (penicillin-sensitive and penicillin-resistant), and Group A beta-haemolytic streptococci.,Appropriate culture and susceptibility studies should be performed to determine susceptibility of the causative organism to cefazolin.
Visual Identification: White or almost white powder filled in 10 ml clear glass vials with grey rubber stoppers sealed with aluminium seal having light rose PP disc; Container Type: Vial; Container Material: Glass Type I Clear; Container Life Time: 12 Months; Container Temperature: Store below 30 degrees Celsius
Registered
2011-12-23
AURO-CEFAZOLIN CONSUMER MEDICINE INFORMATION Ver 1.3 Page 1 of 3 AURO-CEFAZOLIN 0.5G, 1G & 2G Cephazolin (as sodium) CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about AURO- CEFAZOLIN. It does not contain all the available information and does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking AURO- CEFAZOLIN against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT BEING GIVEN THIS MEDICINE ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT AURO-CEFAZOLIN IS USED FOR AURO-CEFAZOLIN contains cephazolin (as cephazolin sodium) as the active ingredient. Cephazolin belongs to a group of antibiotics called cephalosporins. AURO-CEFAZOLIN is used to treat serious infections, caused by bacteria, in different parts of the body. It works by killing the bacteria that are causing your infection, including infections of the: • respiratory tract (throat, tonsils, chest and lungs) • nose • skin and soft tissue • genitourinary tract (kidney and bladder) • bone and joint • blood. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY AURO- CEFAZOLIN HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed it for another purpose . AURO-CEFAZOLIN is not recommended for use in premature infants and in infants under one month. This medicine is only available with a doctor’s prescription. There is no evidence that it is addictive. BEFORE YOU TAKE AURO-CEFAZOLIN _ _ _WHEN _ _YOU _ _MUST _ _NOT _ _BE _ _GIVEN _ _AURO-CEFAZOLIN _ YOU MUST NOT BE GIVEN AURO- CEFAZOLIN IF YOU HAVE A KNOWN ALLERGY TO: • cephazolin • any other cephalosporin antibiotic • or a major allergy to penicillin. Signs of an allergic reaction may include shortness of breath, wheezing or difficulty in breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin. YOU MUST NOT B 阅读完整的文件
Product Information: AURO-CEFAZOLIN (Cephazolin for Injection 0.5g, 1g & 2g) Ver 1.4 Page 1 of 9 PRODUCT INFORMATION AURO-CEFAZOLIN 0.5G (0.5 G CEPHAZOLIN AS CEPHAZOLIN SODIUM) POWDER FOR INJECTION AURO-CEFAZOLIN 1G (1 G CEPHAZOLIN AS CEPHAZOLIN SODIUM) POWDER FOR INJECTION AURO-CEFAZOLIN 2G (2 G CEPHAZOLIN AS CEPHAZOLIN SODIUM) POWDER FOR INJECTION NAME OF THE MEDICINE The name of the medicine is cephazolin as cephazolin sodium. CHEMICAL NAME: Sodium (6 _R_ ,7 _R_ )-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)sulphanyl]methyl]-8-oxo- 7-[(1 _H_ -tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. MOLECULAR FORMULA: C 14 H 13 N 8 NaO 4 S 3 MOLECULAR WEIGHT: 476.5 CAS REGISTRY NUMBER: _[27164-46-1]_ DESCRIPTION AURO-CEFAZOLIN is a semisynthetic cephalosporin antibiotic for parenteral administration only. It is a white or almost white powder, very hygroscopic. It is freely soluble in water and very slightly soluble in ethanol. It contains approximately 48 mg (2.1 mEq) of sodium per g of cephazolin sodium Microbiology: In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell-wall synthesis. Cephazolin is active against the following organisms in vitro: _ _ _Staphylococcus aureus _ (penicillin-sensitive and penicillin-resistant). Group A beta-haemolytic streptococci and other strains of streptococci (many strains of enterococci are resistant). _ _ _Streptococcus pneumoniae _ _ _ _Klebsiella species _ _Escherichia coli _ _ _ _ _ _Enterobacter aerogenes _ _Proteus mirabilis _ _ _ _ _ _Haemophilus influenzae _ Most strains of _Enterobacter cloacae _ and indole-positive _Proteus (Pr. vulgaris, Pr. morganii, Pr. _ _rettgeri) _ are resistant. Methicillin-resistant staphylococci, _Serratia, Pseudomonas, Acinetobacter _ _calcoaceticus _ (formerly _Mima _ and _Herellea _ species) are almost uniformly resistant to cephazolin. Product Information: AURO-CEFAZOLIN (Cephazolin for Injection 0.5g, 1g & 2g) Ver 1.4 Page 2 of 9 Pharmacology: The following table demonst 阅读完整的文件