资料单张
CMI0041-08
1
ASASANTIN
SR SUSTAINED RELEASE
CAPSULES
_Dipyridamole and Aspirin _
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Asasantin SR.
It does not contain all available
information.
It does not take the place of talking to
your doctor or pharmacist.This leaflet
was last updated on the date at the end
of this leaflet. More recent
information may be available. The
latest Consumer Medicine
Information is available from your
pharmacist, doctor, or from
www.medicines.org.au and may
contain important information about
the medicine and its use of which you
should be aware.
ASK YOUR DOCTOR OR PHARMACIST IF
YOU HAVE ANY CONCERNS OR QUESTIONS
ABOUT TAKING THIS MEDICINE,
KEEP THIS INFORMATION WITH YOUR
CAPSULES.
You may need to read it again.
WHAT ASASANTIN SR IS
USED FOR
Asasantin SR helps to prevent
recurrence of stroke in people who
have had a previous stroke or transient
ischaemic attack (TIA).
Asasantin SR works by preventing
blood clots from forming. The ability
of Asasantin SR to prevent blood clots
is due to its effect on blood cells
known as platelets.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY THIS MEDICINE
HAS BEEN PRESCRIBED FOR YOU.
Your doctor may have prescribed it
for another reason
BEFORE YOU TAKE
ASASANTIN SR
_WHEN YOU MUST NOT TAKE IT _
DO NOT TAKE ASASANTIN SR IF YOU
HAVE AN ALLERGY TO:
aspirin, or NSAIDs, non-steroidal
anti-inflammatory medicines
dipyridamole
any of the other ingredients listed
at the end of this leaflet.
Some of the symptoms of an allergic
reaction may include:
shortness of breath
wheezing or difficulty breathing
swelling of the face, lips, tongue
or other parts of the body
rash, itching or hives on the skin
DO
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产品特点
PI0069-09
1
ASASANTIN
SR
SUSTAINED-RELEASE CAPSULES
NAME OF THE MEDICINE
ASASANTIN
SR sustained-release capsules contain the active ingredients
dipyridamole and
aspirin.
The structural formulae for dipyridamole and aspirin are as follows:
Dipyridamole
Aspirin
_DIPYRIDAMOLE _
An odourless, yellow crystalline powder with a bitter taste. It has
a melting point in the range of
164-168
C, and is soluble in dilute acids, methanol, ethanol
and chloroform. The molecular
formula for dipyridamole is C
24
H
40
N
8
O
4
and the molecular weight is 504.6. The chemical name for
dipyridamole is
2,6-bis(diethanolamino)-4,8-dipiperidino-pyrimido[5,4-d]pyrimidine.
The CAS
number is 58-32-2.
_ASPIRIN _
A white crystalline powder or colourless crystals, odourless
or almost odourless, slightly soluble in
water, freely soluble in alcohol, soluble in chloroform and
in ether. It melts at about 143
C. The
molecular formula for aspirin is C
9
H
8
O
4
and the molecular weight is 180.2. Aspirin is commonly
known as acetylsalicylic acid. The chemical name is
2-acetoxybenzoic acid. The CAS number is
50-78-2.
DESCRIPTION
Each ASASANTIN
SR sustained-release capsule contains dipyridamole 200 mg and
aspirin
25 mg. The inactive ingredients in ASASANTIN
SR sustained-release capsules are: tartaric
acid, povidone, methacrylic acid copolymer (Eudragit S 100), talc,
acacia, hypromellose,
hypromellose phthalate, glycerol triacetate, dimethicone 350,
stearic acid, lactose, aluminium
stearate, colloidal anhydrous silica, maize starch, microcrystalline
cellulose, sucrose, gelatin,
titanium dioxide, iron oxide red CI77491 and iron oxide yellow
CI77492.
PHARMACOLOGY
Dipyridamole has an antithrombotic action based on its ability to
modify various aspects of platelet
function. It causes inhibition of platelet adhesion and
aggregation, particularly in diseased states
where platelet
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