国家: 马来西亚
语言: 英文
来源: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
HYDROCHLOROTHIAZIDE
PHARMAFORTE (MALAYSIA) SDN. BHD.
HYDROCHLOROTHIAZIDE
30 Tablets
APOTEX INC. - ETOBICOKE SITE
APO-HYDROCHLOROTHIAZIDE TABLET _CONSUMER MEDICATION INFORMATION LEAFLET_ Hydrochlorothiazide (25mg,50mg) 1 WHAT IS IN THIS LEAFLET 1. What Apo-Hydrochlorothiazide is used for 2. How Apo-Hydrochlorothiazide works 3. Before you use Apo- Hydrochlorothiazide 4. How to use Apo- Hydrochlorothiazide 5. While you are using it 6. Side effects 7. Storage and Disposal of Apo- Hydrochlorothiazide 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT APO-HYDROCHLOROTHIAZIDE IS USED FOR Hydrochlorothiazide treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. This medication is also used to treat high blood pressure (hypertension). HOW APO-HYDROCHLOROTHIAZIDE WORKS Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from reabsorbing too much salt in the kidney, which can cause fluid retention. BEFORE YOU USE APO- HYDROCHLOROTHIAZIDE - _When you must not use it _ Do not use this product if you are allergic to hydrochlorothiazide, or any ingredients in this medication. _Pregnancy and lactation _ Do not take Apo- Hydrochlorothiazide if you are pregnant, trying to get pregnant or think you may be pregnant. Do not take Apo- Hydrochlorothiazide if you are breast-feeding. Ask your doctor or pharmacist for advice before taking any medicine. _ _ _ _ - _Before you start to use it _ Before you start to use Apo- Hydrochlorothiazide, your doctor should know if you have any other medical conditions, for example impaired liver function, electrolyte imbalance and gout. You should also let your doctor know if you have any history of allergy or bronchial asthma. - _Taking other medicines _ _ _ Some medications might cause complications when taken together with Apo-Hydrochlorothiazide. These medications include steroid or adrenocorticotropic hormone [ACTH] (hypokalaemia/ low potassium levels), thiazides, insulins (requiring a change of dose), diuretics (increase 阅读完整的文件
APO-HYDROCHLOROTHIAZIDE HYDROCHLOROTHIAZIDE TABLETS USP 25MG AND 50MG DIURETIC ANTIHYPERTENSIVE PHARMACOLOGY : Hydrochlorothiazide inhibits reabsorption of sodium and chloride in the distal tubule thus promoting water loss. The higher urine volume increases potassium loss, therefore restricting salt intake decreases potassium loss. Oral doses are well absorbed and reach peak effect in about 4 hours, with a 6 to 12 hours duration. It is excreted unchanged in the urine with a half-life of 3 to 5 hours. The mild blood pressure reducing effects are initially due to volume reduction but the persisting effect includes other undetermined mechanisms that reduce peripheral resistance. A high salt intake reverse its antihypertensive effect. INDICATIONS : Adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, corticosteroid and estrogen therapy and in edema of renal origin (i.e. nephrotic syndrome, acute glomerulonephritis, chronic renal disease). In the management of hypertension, hydrochlorothiazide may be used alone or as an adjunct to other antihypertensive drugs. Since it enhances the action of these agents, their dosage must be reduced to avoid an excessive drop in blood pressure and other adverse effects. CONTRAINDICATIONS : Anuria; discontinue if increasing azotemia and oliguria occur during treatment of severe progressive renal disease. Do not use in patients known to be sensitive to thiazides or other sulfonamide derived drugs. PRECAUTIONS : May precipitate or increase azotemia; cumulative effects may develop in presence of impaired renal function; discontinue if increasing azotemia and oliguria occur during treatment of severe progressive renal disease. Use with caution in impaired hepatic function or progressive liver disease since minor alterations of fluid and electrolyte balance or of serum ammonia may precipitate hepatic coma. The possibility of sensitivity reaction should be considered in patients with or without a history of allergy or bronchial asthma. The possibility of 阅读完整的文件