国家: 印度尼西亚
语言: 印度尼西亚文
来源: Badan Pengawas Obat dan Makanan RI - Indonesian Food and Drug Supervisory Agency
ISOFLURANE
KALBE FARMA - Indonesia
ISOFLURANE
250 ML
CAIRAN INHALASI
DUS, BOTOL @ 250 ML
BAXTER HEALTHCARE CORPORATION - United States of America
2022-01-03
PRESENTATION AERRANE (Isoflurane USP) is a colourless, volatile liquid for inhalation, containing 100% Isoflurane USP. INDICATIONS AERRANE is a volatile halogenated anaesthetic for general inhalation anaesthesia. DOSAGE AND ADMINISTRATION In order to be able to accurately control the precise concentration of AERRANE, vaporisers that have been specifically calibrated for isoflurane should be used. Minimum alveolar concentration (MAC) of AERRANE in humans: AGE (YEARS) O 2 - 100% O 2 + N 2 0 (60%) Neonates 1.60 - - 1 - 6 months 1.87 - - 7 - 11 months 1.80 - - 1 - 2 years 1.60 - - 3 - 5 years 1.62 - - 6 - 10 years 1.40 0.58 10 - 15 years 1.16 0.53 AGE (YEARS) O 2 - 100% O 2 + N 2 0 (70%) 26 ± 4 1.28 0.56 44 ± 7 1.15 0.50 64 ± 5 1.05 0.37 INDUCTION OF ANAESTHESIA: If AERRANE is used for induction of anaesthesia, a starting concentration of 0.5% is recommended. Concentrations of 1.3 - 3.0% usually bring about surgical anaesthesia within 7 to 10 minutes. It is recommended that use be made of a hypnotic dose of a short acting barbiturate or another product such as propofol, etomidate, or midazolam in order to avoid coughing or laryngospasm, which can arise if induction is carried out with AERRANE alone or in combination with oxygen or with an oxygen-nitrous oxide mixture. MAINTENANCE OF ANAESTHESIA: Anaesthesia can be maintained during surgery using a concentration of 1.0-2.5%, with the simultaneous administration of N 2 0 and O 2 . A higher concentration of 1.5 - 3.5% of AERRANE is necessary if AERRANE is administered with pure oxygen. RECOVERY The concentration of AERRANE must be reduced to 0.5% at the end of the operation, or to 0% during closure of the wound to allow prompt recovery. If all administration of anaesthetic agents has been stopped, the air passages of the patient should be ventilated several times with 100% oxygen until complete awakening occurs. If the vector gas is a mixture of 50% O 2 and 50% N 2 O, the volume of the minimum alveolar concentration of AERRANE is approximately 0.65%. CONTRAINDICATION 阅读完整的文件