適癲痛膜衣錠 50 毫克

国家: 台湾

语言: 中文

来源: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)

有效成分:

TOPIRAMATE

可用日期:

永信藥品工業股份有限公司 台中市大甲區頂店里中山路一段1191號 (56065601)

ATC代码:

N03AX11

药物剂型:

膜衣錠

组成:

TOPIRAMATE (9200038300) MG

每包单位数:

塑膠瓶裝;;PTP 鋁箔盒裝;;AL-AL鋁箔盒裝

类:

製　劑

处方类型:

須由醫師處方使用

厂商:

永信藥品工業股份有限公司台中幼獅廠 台中市大甲區日南里工九路27號 TW

治疗领域:

topiramate

疗效迹象:

用於成人及二歲以上兒童局部癲癇或併有Lennox-Gastaut症候群之癲癇及原發性全身性強直陣攣癲癇的輔助治療，用於Partial Onset Seizure病人之單一藥物治療，預防偏頭痛。

產品總結:

有效日期: 2028/12/01; 英文品名: Toramate Film Coated Tablets 50mg

授权日期:

2008-12-01

资料单张

Topiramate
Topiramate
Topiramate
Topiramate
Topiramate
Topiramate
valproic acid
Topiramate
Topiramate
AEDs
Topiramate
Topiramate
Topiramate
Topiramate
Topiramate
Topiramate
Topiramate
Topiramate
15 %
TOPIRAMATE
Topiramate
(phenytoin
carbamazepine
valproic acid
phenobarbital
primidone)
Topiramate
phenytoin
phenytoin
(CYP2C19)
phenytoin
phenytoin
100
400 mg/day
Topiramate
lamotrigine
lamotrigine
TOPIRAMATE
Phenytoin
carbamazepine
Topiramate
Topiramate
phenytoin
carbamazepine
Topiramate
Topiramate
Valproic acid
Topiramate
Topiramate
↔
<15%
NS
AED
DIGOXIN
Topiramate
digoxin
(AUC)
12%
digoxin
Topiramate
digoxin
Topiramate
Topiramate
1 mg norethindrene(NET)
35 mcg ethinyl estradiol(EE)
Topiramate
Topiramate
50
200 mg/day
Topiramate
AUC
valproic
acid
Topiramate
Topiramate
200
400
800 mg/day
EE
AUC
18% 21% 30%
Topiramate 50 mg/day
800 mg/day
NET
AUC
Topiramate
200
800 mg/day
EE
AUC
Topiramate
50
200 mg/day
EE
AUC
Topiramate
estrogen
LITHIUM
lithium Topiramate 200 mg/day
lithium
(18% for AUC)
lithium Topiramate 200 mg/day
lithium
Topiramate
600 mg/day
(26% for
AUC)
Topiramate
lithium
RISPERIDONE
Topiramate
100
250
400 mg/day
risperidone
1
6 mg/day
(steady-state AUC
250 mg/day
400 mg/day
16%
33%)
(risperidone
9-hydroxyrisperidone)
9-hydroxyrisperidone
Risperidone
Topiramate
HYDROCHLOROTHIAZIDE(HCTZ)
HCTZ
25 mg
24
Topiramate
96 mg
12
HCTZ
Topiramate
Topiramate
C
max
27% AUC
29%
HCTZ
Topiramate
Topiramate
HCTZ
Topiramate
Topiramate
HCTZ
HCTZ
Topiramate
METFORMIN
metformin
metformin
Topiramate
metformin
Topiramate
metformin
Topiramate
metformin
C
max
AUC
0-12h
18% 25%
CL/F
20% Topiramate
metformin
t
max
Topiramate
metformin
metformin
Topiramate
Metformin
Topiramate
metformin
Topiramate
PIOGLITAZONE
Topiramate
pioglitazone
pioglitazone
AUC
,ss
15% C
max,ss
hydroxy-
C
max,ss
AUC
,ss
13% 16%
keto-
C
max,ss
AUC
, s s
60%
To p i r a m a t e
p i o g l i t a z o n e
p i o g l i t a z o n e
Topiramate
GLYBURIDE
glyburide(5mg/day)
Topiramate(150 mg/day)
Topiramate
glyburide
AUC
24
25%
4 - t r a n s - h y d r o x y - g l y b u r i d